产品名称 | Sonepiprazole hydrochloride - PNU 101387 |
产品货号 | Axon 2115 CAS [170857-36-0] MF C21H27N3O3S.HClMW 437.98 Purity: 98% Optical purity: Optically pure Soluble in DMSO Description Selective dopamine D4 antagonist; Displayed high affinity (Ki = 10 nM) and selectivity for the D4 receptor expressed in clonal cell lines, lacking measurable affinity for other dopamine receptors, and noradrenalin, serotonin and histamine receptor families (Ki > 2000 nM) References Certificates Categories Extra info PA Broderick et al. Clozapine, haloperidol, and the D4 antagonist PNU-101387G: in vivo effects on mesocortical, mesolimbic, and nigrostriatal dopamine and serotonin release. J. Neural. Transm. 1998, 105(6-7), 749-767. KM Merchant et al. Pharmacological characterization of U-101387, a dopamine D4 receptor selective antagonist. J. Pharmacol. Exp. Ther. 1996, 279(3), 1392-1403. Certificate of Analysis Material Safety Data Sheet CNS D4 A17 Pfizer Licensed Products Selective dopamine D4 antagonist Chemical name (S)-4-(4-(2-(isochroman-1-yl)ethyl)piperazin-1-yl)benzenesulfonamide hydrochloride Source information Pfizer compound; Sold for research purposes under agreement from Pfizer Inc. Parent CAS No. [170858-33-0] Order Size Unit Price Stock 5 mg €85.00 In Stock |
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产品品牌 | axonmedchem |
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Sonepiprazole hydrochloride - PNU 101387Axon 2115 CAS [170857-36-0] MF C21H27N3O3S.HCl
Description
Selective dopamine D4 antagonist; Displayed high affinity (Ki = 10 nM) and selectivity for the D4 receptor expressed in clonal cell lines, lacking measurable affinity for other dopamine receptors, and noradrenalin, serotonin and histamine receptor families (Ki > 2000 nM)
Selective dopamine D4 antagonist
Chemical name(S)-4-(4-(2-(isochroman-1-yl)ethyl)piperazin-1-yl)benzenesulfonamide hydrochloride Source informationPfizer compound; Sold for research purposes under agreement from Pfizer Inc.Parent CAS No.[170858-33-0] |
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