产品名称 | UNC 9994 hydrochloride |
产品货号 | Axon 2562 CAS [N.A.] MF C21H22Cl2N2OS.HClMW 457.84 Purity: 99% Soluble in DMSO Description Unique, β-arrestin-biased functionally selective dopamine D2 receptor (D2R) agonist (Ki value 30 nM; EC50 value 50 nM in β-arrestin-2 recruitment assay) that exhibits antipsychotic activity in vivo. UNC9994 markedly inhibited PCP-induced hyperlocomotion in wild-type mice, which effect was completely abolished in β-arrestin-2 knockout mice. KEYWORDS: UNC 9994 hydrochloride | supplier | D2 agonist | Axon Medchem | Axon 2562 | UNC9994 | CAS [1354030-51-5] | Dopamine | D2 | Agonist | GPCR | D2R | β-arrestin | beta-arrestin | antipsychotic |
产品价格 | 现货询价,电话:010-67529703 |
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产品品牌 | axonmedchem |
产品概述 | |
产品详情 |
UNC 9994 hydrochlorideAxon 2562 CAS [N.A.] MF C21H22Cl2N2OS.HCl
DescriptionUnique, β-arrestin-biased functionally selective dopamine D2 receptor (D2R) agonist (Ki value 30 nM; EC50 value 50 nM in β-arrestin-2 recruitment assay) that exhibits antipsychotic activity in vivo. UNC9994 markedly inhibited PCP-induced hyperlocomotion in wild-type mice, which effect was completely abolished in β-arrestin-2 knockout mice. KEYWORDS: UNC 9994 hydrochloride | supplier | D2 agonist | Axon Medchem | Axon 2562 | UNC9994 | CAS [1354030-51-5] | Dopamine | D2 | Agonist | GPCR | D2R | β-arrestin | beta-arrestin | antipsychotic
β-Arrestin-biased functionally selective dopamine D2R agonist
Chemical name5-(3-(4-(2,3-dichlorophenyl)piperidin-1-yl)propoxy)benzo[d]thiazole hydrochloride Parent CAS No.[1354030-51-5] |
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