产品名称 | NS 30678 hydrochloride |
产品货号 | Axon 1742 CAS [1193707-19-5] MF C12H16ClNO4S.HClMW 342.24 Purity: 99% Optical purity: Optically pure Soluble in water and DMSO Description Dopamine D2 receptor ligand with surmountable/competitive-like D2 antagonist properties (Ki and IC50 values of value 9.7 nM and 7 nM, repectively in HEK-hD2L-Gαqi5 cells), equipotent to Haloperidol and Risperidone (Axon 1454). NS30678 shows rapid recovery and dopamine responsiveness within 5 min after administration. References Certificates Categories Extra info T. Dyhring et al. The dopaminergic stabilizers pridopidine (ACR16) and (-)-OSU6162 display dopamine D(2) receptor antagonism and fast receptor dissociation properties. Eur J Pharmacol. 2010 Feb 25;628(1-3):19-26. K. Sahlholm et al. Typical and atypical antipsychotics do not differ markedly in their reversibility of antagonism of the dopamine D2 receptor. Int J Neuropsychopharmacol. 2014 Jan;17(1):149-55. Certificate of Analysis Material Safety Data Sheet CNS D2 A17 D2 ligand with surmountable/competitive-like D2 antagonist properties Chemical name (S)-N-((5-chloro-7-(methylsulfonyl)-2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)ethanamine hydrochloride Parent CAS No. [1193707-15-1] Order Size Unit Price Stock 2 mg €115.00 In Stock |
产品价格 | 现货询价,电话:010-67529703 |
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产品品牌 | axonmedchem |
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NS 30678 hydrochlorideAxon 1742 CAS [1193707-19-5] MF C12H16ClNO4S.HCl
DescriptionDopamine D2 receptor ligand with surmountable/competitive-like D2 antagonist properties (Ki and IC50 values of value 9.7 nM and 7 nM, repectively in HEK-hD2L-Gαqi5 cells), equipotent to Haloperidol and Risperidone (Axon 1454). NS30678 shows rapid recovery and dopamine responsiveness within 5 min after administration.
D2 ligand with surmountable/competitive-like D2 antagonist properties
Chemical name(S)-N-((5-chloro-7-(methylsulfonyl)-2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)ethanamine hydrochloride Parent CAS No.[1193707-15-1] |
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