产品名称

OSS-128167

产品货号

Axon 2843 CAS [887686-02-4] MF C19H14N2O6MW 366.32 Purity: 99% Soluble in 0.1N NaOH(aq) and DMSO Description OSS-128167 is a selective SIRT6 inhibitor (IC50 value of 89 µM). KEYWORDS: OSS-128167 | supplier | SIRT 6 inhibitor | OSS128167 | OSS 128167 | CAS [887686-02-4] | Histone | SIRT | Inhibitor | Enzymes | Sirtuin | Diabetes

产品价格

现货询价，电话：010-67529703

产品规格

产品品牌

axonmedchem

产品概述

产品详情

OSS-128167

Based on 3 reference(s) in Google Scholar 8 10 3

Axon 2843

CAS [887686-02-4]

MF C19H14N2O6
MW 366.32

Purity: 99%
Soluble in 0.1N NaOH(aq) and DMSO

OSS-128167

Description

OSS-128167 is a selective SIRT6 inhibitor (IC50 value of 89 µM).

KEYWORDS: OSS-128167 | supplier | SIRT 6 inhibitor | OSS128167 | OSS 128167 | CAS [887686-02-4] | Histone | SIRT | Inhibitor | Enzymes | Sirtuin | Diabetes

MD Parenti et al. Discovery of novel and selective SIRT6 inhibitors. J Med Chem. 2014 Jun 12;57(11):4796-804.

P Damonte et al. SIRT6 inhibitors with salicylate-like structure show immunosuppressive and chemosensitizing effects. Bioorg Med Chem. 2017 Oct 15;25(20):5849-5858.

Cell Cycle Regulation Cell Signaling & Oncology Diabetes & Metabolism Epigenetics Pain & Inflammation DNA-damage Response EC 3.5.1.98 SIRT

Selective SIRT6 inhibitor

Chemical name

5-(3-(Furan-2-carboxamido)benzamido)-2-hydroxybenzoic acid

Parent CAS No.

[887686-02-4]

产品资料