| 产品名称 | RKI 1447 |
| 产品货号 | Axon 2229 CAS [1342278-01-6] MF C16H14N4O2SMW 326.37 Purity: 99% Soluble in DMSO Description Potent inhibitor of the Rho-associated ROCK kinases with anti-invasive and antitumor activities in breast cancer (IC50 values 14.5 and 6.2 nM for ROCK 1 and 2 respectively).RKI 1447 is a Type 1 inhibitor that binds both the hinge region and the DFG motif of the ROCK ATP binding site. References Certificates Categories Extra info R.A. Patel et al. RKI-1447 is a potent inhibitor of the Rho-associated ROCK kinases with anti-invasive and antitumor activities in breast cancer. Cancer Res. 2012, 72, 5025-5034. Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology Stem Cell ROCK TGF-β EC 2.7.11.1 Potent inhibitor of the Rho-associated ROCK kinases Chemical name 1-(3-hydroxybenzyl)-3-(4-(pyridin-4-yl)thiazol-2-yl)urea Parent CAS No. [1342278-01-6] Order Size Unit Price Stock 10 mg €105.00 In Stock |
| 产品价格 | 现货询价，电话：010-67529703 |
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| 产品品牌 | axonmedchem |
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RKI 1447Axon 2229 CAS [1342278-01-6] MF C16H14N4O2S
Description
Potent inhibitor of the Rho-associated ROCK kinases with anti-invasive and antitumor activities in breast cancer (IC50 values 14.5 and 6.2 nM for ROCK 1 and 2 respectively).RKI 1447 is a Type 1 inhibitor that binds both the hinge region and the DFG motif of the ROCK ATP binding site.
Potent inhibitor of the Rho-associated ROCK kinases
Chemical name1-(3-hydroxybenzyl)-3-(4-(pyridin-4-yl)thiazol-2-yl)urea Parent CAS No.[1342278-01-6] |
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