| 产品名称 | HA 14-1 |
| 产品货号 | Axon 2007 CAS [65673-63-4] MF C17H17BrN2O5MW 409.23 Purity: 98% Soluble in DMSO and Ethanol Description Bcl-2 antagonist and apoptosis inducer of tumor cells; HA14-1 induces the activation of Apaf-1 and caspases. References Certificates Categories Extra info JL Wang et al. Structure-based discovery of an organic compound that binds Bcl-2 protein and induces apoptosis of tumor cells. PNAS 2000, 97(13), 7124-7129. J Skommen et al. HA14-1, a small molecule Bcl-2 antagonist, induces apoptosis and modulates action of selected anticancer drugs in follicular lymphoma B cells. Leukemia Res. 2006, 30(3), 322–331. JM Doshi et al. Structure-activity relationship studies of ethyl 2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate (HA 14-1), an antagonist for antiapoptotic Bcl-2 proteins to overcome (...). J. Med. Chem. 2006, 49(26), 7731-7739. Certificate of Analysis Material Safety Data Sheet Apoptosis Cell Cycle Regulation Cell Signaling & Oncology Bcl Bcl-2 inhibitor and apoptosis inducer of tumor cells Chemical name ethyl 2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate Parent CAS No. [65673-63-4] Order Size Unit Price Stock 10 mg €75.00 In Stock |
| 产品价格 | 现货询价，电话：010-67529703 |
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| 产品品牌 | axonmedchem |
| 产品概述 | |
| 产品详情 |
HA 14-1Axon 2007 CAS [65673-63-4] MF C17H17BrN2O5
Description
Bcl-2 antagonist and apoptosis inducer of tumor cells; HA14-1 induces the activation of Apaf-1 and caspases.
Bcl-2 inhibitor and apoptosis inducer of tumor cells
Chemical nameethyl 2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate Parent CAS No.[65673-63-4] |
| 产品资料 |
