产品名称 CID 1067700
产品货号 Axon 2184 CAS [314042-01-8] MF C18H18N2O4S2MW 390.48 Purity: 99% Soluble in DMSO Description First inhibitor of Rab7 GTPase exhibiting significant inhibitory potency on Rab7 nucleotide binding with nanomolar inhibitor (Ki) values and an inhibitory response of ≥97% for BODIPY-GTP and BODIPYGDP binding (Ki values 13 nM and 19 nM, and EC50 values 11 and 21 nM, respectively). CID 1067700 is a competitive guanine nucleotide binding inhibitor characterized for the Ras-super family of GTPases. References Certificates Categories Extra info J.O. Agola et al. A competitive nucleotide binding inhibitor: in vitro characterization of Rab7 GTPase inhibition. ACS Chem. Biol. 2012, 7, 1095-1108. Certificate of Analysis Material Safety Data Sheet Apoptosis Cell Cycle Regulation Cell Signaling & Oncology Epigenetics Immunology MAPK EC 3.6.5.2 Rab7 First inhibitor of Rab7 GTPase Chemical name 2-(3-benzoylthioureido)-5,5-dimethyl-5,7-dihydro-4H-thieno[2,3-c]pyran-3-carboxylic acid Parent CAS No. [314042-01-8] Order Size Unit Price Stock 10 mg €125.00 In Stock
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CID 1067700

Based on 14 reference(s) in Google Scholar 8 10 14

Axon 2184

CAS [314042-01-8]

MF C18H18N2O4S2
MW 390.48

  • Purity: 99%
  • Soluble in DMSO

CID 1067700

Description

First inhibitor of Rab7 GTPase exhibiting significant inhibitory potency on Rab7 nucleotide binding with nanomolar inhibitor (Ki) values and an inhibitory response of ≥97% for BODIPY-GTP and BODIPYGDP binding (Ki values 13 nM and 19 nM, and EC50 values 11 and 21 nM, respectively). CID 1067700 is a competitive guanine nucleotide binding inhibitor characterized for the Ras-super family of GTPases.

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