产品名称

PDE9A inhibitor C33(S) - (S)-C33

产品货号

Axon 2825 CAS [2066488-39-7] MF C18H20ClN5OMW 357.84 Purity: 98% Optical purity: Optically pure Soluble in DMSO Description (S)-C33 is a potent and selective PDE9A inhibitor with an IC50 value of 11 nM. KEYWORDS: PDE9A inhibitor C33(S) | supplier | PDE9A inhibitor | (S)-C33 | CAS [2066488-39-7] | cGMP | PDE | Inhibitor | Enzymes | PDE9 | PDE9A

产品价格

现货询价，电话：010-67529703

产品规格

产品品牌

axonmedchem

产品概述

产品详情

PDE9A inhibitor C33(S) - (S)-C33

Based on 1 reference(s) in Google Scholar 8 10 1

Axon 2825

CAS [2066488-39-7]

MF C18H20ClN5O
MW 357.84

Purity: 98%
Optical purity: Optically pure
Soluble in DMSO

PDE9A inhibitor C33(S)

Description

(S)-C33 is a potent and selective PDE9A inhibitor with an IC50 value of 11 nM.

KEYWORDS: PDE9A inhibitor C33(S) | supplier | PDE9A inhibitor | (S)-C33 | CAS [2066488-39-7] | cGMP | PDE | Inhibitor | Enzymes | PDE9 | PDE9A

M Huang et al. Structural Asymmetry of Phosphodiesterase-9A and a Unique Pocket for Selective Binding of a Potent Enantiomeric Inhibitor. Mol Pharmacol. 2015 Nov;88(5):836-45.

PX Wang et al. C33(S), a novel PDE9A inhibitor, protects against rat cardiac hypertrophy through upregulating cGMP signaling. Acta Pharmacol Sin. 2017 Sep;38(9):1257-1268.

CNS Diabetes & Metabolism EC 3.1.4.35 PDE

Potent and selective PDE9A inhibitor

Chemical name

(S)-6-(1-(4-Chlorophenyl)ethylamino)-1-cyclopentyl-1H-pyrazolo[3,4-d]pyrimidin-4(7H)-one

Parent CAS No.

[2066488-39-7]

产品资料