| 产品名称 | Tienilic Acid - Ticrynafan |
| 产品货号 | Axon 1564 CAS [40180-04-9] MF C13H8Cl2O4SMW 331.17 Purity: 99% Soluble in DMSO Description Tienilic acid was found to act as a suicide substrate at the cytochrome P450 enzymes involved in drug metabolism. It is a good mechanism based inhibitor of CYP2C9 and seems to inactivate it stoichiometrically References Certificates Categories Extra info JW Manier et al. Hepatotoxicity associated with ticrynafen – a uricosuric diuretic. Am. J. Gastroenterol. 1982, 77(6), 401–4. P Jean et al. Oxidation of tienilic acid by human yeast-expressed cytochromes P450 2C8, 2C9, 2C18 and 2C19: Evidence that this drug is a mechanism-based inhibitor specific of cytochrome P450 2C9. Eur. J. Biochem. 1996, 241 797-804. Certificate of Analysis Material Safety Data Sheet Diabetes & Metabolism Miscellaneous EC 1.14.13.80 Cytochrome P450 CYP2C10 Inhibitor Chemical name [2,3-Dichloro-4-(thiophene-2-carbonyl)-phenoxyl]-acetic acid Parent CAS No. [40180-04-9] Order Size Unit Price Stock 5 mg €75.00 In Stock |
| 产品价格 | 现货询价，电话：010-67529703 |
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| 产品品牌 | axonmedchem |
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Tienilic Acid - TicrynafanAxon 1564 CAS [40180-04-9] MF C13H8Cl2O4S
Description
Tienilic acid was found to act as a suicide substrate at the cytochrome P450 enzymes involved in drug metabolism. It is a good mechanism based inhibitor of CYP2C9 and seems to inactivate it stoichiometrically
CYP2C10 Inhibitor
Chemical name[2,3-Dichloro-4-(thiophene-2-carbonyl)-phenoxyl]-acetic acid Parent CAS No.[40180-04-9] |
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