产品名称 | Danoprevir - ITMN 191 | RG 7227 | R 7227 |
产品货号 | Axon 1669 CAS [850876-88-9] MF C35H46FN5O9SMW 731.83 Purity: 99% Optical purity: Optically pure Soluble in DMSO Description Potent and orally active inhibitor of hepatitis C virus (HCV) NS3/4A serine protease (replicon IC50: 1.6 nM) References Certificates Categories Extra info EJ Gane et al. Antiviral activity, safety, and pharmacokinetics of danoprevir / ritonavir plus PEG-IFN α-2a/RBV in hepatitis C patients. J Hepatol. 2011, 55(5), 972-979. Certificate of Analysis Material Safety Data Sheet Immunology Miscellaneous HCV NS3 Serine Protease HCV NS4A Serine Protease EC 3.4.21.98 HCV NS3/4A serine protease inhibitor Chemical name (2R,6S,13aS,14aR,16aS,Z)-6-(tert-butoxycarbonylamino)-14a-(cyclopropylsulfonylcarbamoyl)-5,16-dioxo-1,2,3,5,6,7,8,9,10,11,13a,14,14a,15,16,16a-hexadecahydrocyclopropa[e]pyrrolo[1,2-a][1,4]diazacyclopentadecin-2-yl 4-fluoroisoindoline-2-carboxylate Parent CAS No. [850876-88-9] Order Size Unit Price Stock 2 mg €115.00 In Stock |
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产品品牌 | axonmedchem |
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Danoprevir - ITMN 191 | RG 7227 | R 7227Axon 1669 CAS [850876-88-9] MF C35H46FN5O9S
Description
Potent and orally active inhibitor of hepatitis C virus (HCV) NS3/4A serine protease (replicon IC50: 1.6 nM)
HCV NS3/4A serine protease inhibitor
Chemical name(2R,6S,13aS,14aR,16aS,Z)-6-(tert-butoxycarbonylamino)-14a-(cyclopropylsulfonylcarbamoyl)-5,16-dioxo-1,2,3,5,6,7,8,9,10,11,13a,14,14a,15,16,16a-hexadecahydrocyclopropa[e]pyrrolo[1,2-a][1,4]diazacyclopentadecin-2-yl 4-fluoroisoindoline-2-carboxylate Parent CAS No.[850876-88-9] |
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