| 产品名称 | TAS-103 dihydrochloride - BMS 247615 dihydrochloride |
| 产品货号 | Axon 2914 CAS [174634-09-4] MF C20H19N3O2.2HClMW 406.31 Purity: 99% Soluble in water and DMSO Description TAS-103 dihydrochloride is an anticancer agent targeting topoisomerases I and II with IC50 values of 2 µM and 6.5 µM, respectively. Moreover, TAS-103 dihydrochloride has a strong cytotoxic effect on P388 and KB cells with IC50 values of 0.0011 µM and 0.0096 µM, respectively. Also, TAS-103 has strong inhibitory effects on the growth of various mouse and human solid tumors in vivo, as well as high antitumor activity against lung metastatic cancer. KEYWORDS: TAS-103 dihydrochloride | supplier | Topo 1/2 inhibitor | BMS 247615 dihydrochloride | TAS-103 | TAS103 | BMS247615 | BMS-247615 | CAS [174634-08-3] | CAS [174634-09-4] | DNA-RNA | TOPO | Inhibitor | Enzymes | Topoisomerase | Lung cancer |
| 产品价格 | 现货询价，电话：010-67529703 |
| 产品规格 | |
| 产品品牌 | axonmedchem |
| 产品概述 | |
| 产品详情 |
TAS-103 dihydrochloride - BMS 247615 dihydrochlorideAxon 2914 CAS [174634-09-4] MF C20H19N3O2.2HCl
DescriptionTAS-103 dihydrochloride is an anticancer agent targeting topoisomerases I and II with IC50 values of 2 µM and 6.5 µM, respectively. Moreover, TAS-103 dihydrochloride has a strong cytotoxic effect on P388 and KB cells with IC50 values of 0.0011 µM and 0.0096 µM, respectively. Also, TAS-103 has strong inhibitory effects on the growth of various mouse and human solid tumors in vivo, as well as high antitumor activity against lung metastatic cancer. KEYWORDS: TAS-103 dihydrochloride | supplier | Topo 1/2 inhibitor | BMS 247615 dihydrochloride | TAS-103 | TAS103 | BMS247615 | BMS-247615 | CAS [174634-08-3] | CAS [174634-09-4] | DNA-RNA | TOPO | Inhibitor | Enzymes | Topoisomerase | Lung cancer
Dual inhibitor of topoisomerase I (Topo 1) and topoisomerase II (Topo 2)
Chemical name6-(2-(Dimethylamino)ethylamino)-3-hydroxy-7H-indeno[2,1-c]quinolin-7-one dihydrochloride Parent CAS No.[174634-08-3] |
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