产品名称 ThioLox - Thiophene A9
产品货号 Axon 2844 CAS [1202193-89-2] MF C15H18N2OSMW 274.38 Purity: 99% Soluble in DMSO Description Inhibitor of 15-lipoxygenase-1 (15-LOX-1) with both anti-inflammatory and neuroprotective properties (IC50 value of 12 µM). Ex vivo biological evaluation in precision-cut lung slices (PCLS) showed inhibition of pro-inflammatory gene expression and in vitro studies on neuronal HT-22 cells showed a strong protection against glutamate toxicity for this 15-LOX-1 inhibitor. KEYWORDS: Thiolox | supplier | Lipoxygenase inhibitor | CAS [1202193-89-2] | Fatty acid (Arachidonic acid) | LOX | Inhibitor | Enzymes
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ThioLox - Thiophene A9

Based on 3 reference(s) in Google Scholar 8 10 3

Axon 2844

CAS [1202193-89-2]

MF C15H18N2OS
MW 274.38

  • Purity: 99%
  • Soluble in DMSO

ThioLox

Description

Inhibitor of 15-lipoxygenase-1 (15-LOX-1) with both anti-inflammatory and neuroprotective properties (IC50 value of 12 µM). Ex vivo biological evaluation in precision-cut lung slices (PCLS) showed inhibition of pro-inflammatory gene expression and in vitro studies on neuronal HT-22 cells showed a strong protection against glutamate toxicity for this 15-LOX-1 inhibitor.

KEYWORDS: Thiolox | supplier | Lipoxygenase inhibitor | CAS [1202193-89-2] | Fatty acid (Arachidonic acid) | LOX | Inhibitor | Enzymes

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