产品名称 PF 06465469
产品货号 Axon 2110 CAS [1407966-77-1] MF C30H33N7O2MW 523.63 Purity: 99% Optical purity: Optically pure Soluble in DMSO Description Potent, covalent inhibitor of interleukin-2 inducible T cell kinase (ITK) with nanomolar potency References Certificates Categories Extra info CW Zapf et al. Covalent Inhibitors of Interleukin-2 Inducible T Cell Kinase (Itk) with Nanomolar Potency in a Whole-Blood Assay. J. Med. Chem. 2012, 55(22), 10047-10063.  Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology Immunology ITK EC 2.7.10.2 Pfizer Licensed Products Inhibitor of interleukin-2 inducible T cell kinase (ITK) Chemical name (R)-3-(1-(1-acryloylpiperidin-3-yl)-4-amino-1H-pyrazolo[3,4-d]pyrimidin-3-yl)-N-(4-isopropyl-3-methylphenyl)benzamide Source information Pfizer compound; Sold for research purposes under agreement from Pfizer Inc. Parent CAS No. [1407966-77-1] Order Size Unit Price Stock 5 mg €105.00 In Stock
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PF 06465469

Based on 8 reference(s) in Google Scholar 9 10 8

Axon 2110

CAS [1407966-77-1]

MF C30H33N7O2
MW 523.63

  • Purity: 99%
  • Optical purity: Optically pure
  • Soluble in DMSO

PF 06465469

Description

Potent, covalent inhibitor of interleukin-2 inducible T cell kinase (ITK) with nanomolar potency
Inhibitor of interleukin-2 inducible T cell kinase (ITK)

Chemical name

(R)-3-(1-(1-acryloylpiperidin-3-yl)-4-amino-1H-pyrazolo[3,4-d]pyrimidin-3-yl)-N-(4-isopropyl-3-methylphenyl)benzamide

Source information

Pfizer compound; Sold for research purposes under agreement from Pfizer Inc.

Parent CAS No.

[1407966-77-1]

产品资料