产品名称 Nilotinib - AMN 107 | Tasigna
产品货号 Axon 1396 CAS [641571-10-0] MF C28H22F3N7OMW 529.52 Purity: 99% Soluble in DMSO Description A highly selective inhibitor of Bcr-Abl, the definitive cause of Ph+ CML, and its mutations References Certificates Categories Extra info H Kantarjian et al. Nilotinib in imatinib-resistant CML and Philadelphia chromosome-positive ALL. N. Engl. J. Med. 2006, 354 (24), 2542–51.   E Weisberg et al. AMN107 (nilotinib): a novel and selective inhibitor of BCR-ABL. Br. J. Cancer 2006, 94, 1765-1769.   JM Goldman, JV Melo. BCR-ABL in Chronic Myelogenous Leukemia - How Does It Work? Acta Haematol. 2008, 119, 212-217. Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology BCR-ABL Oncogene Fusion Proteins EC 2.7.10.1 BCR-ABL inhibitor Chemical name 4-methyl-N-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino] benzamide Parent CAS No. [641571-10-0] Order Size Unit Price Stock 5 mg €70.00 In Stock
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Nilotinib - AMN 107 | Tasigna

Based on 8 reference(s) in Google Scholar 9 10 8

Axon 1396

CAS [641571-10-0]

MF C28H22F3N7O
MW 529.52

  • Purity: 99%
  • Soluble in DMSO

Nilotinib

Description

A highly selective inhibitor of Bcr-Abl, the definitive cause of Ph+ CML, and its mutations
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