产品名称 | UK 356618 - PF 03890101 |
产品货号 | Axon 2111 CAS [230961-08-7] MF C34H43N3O4MW 557.72 Purity: 98% Optical purity: Optically pure Soluble in DMSO Description Potent and selective matrix metalloprotease-3 (MMP-3 aka stromelysin-1) inhibitor (IC50=5.9 nM); >140-fold selective over MMP-1, MMP-2, MMP-9 and MMP-14 References Certificates Categories Extra info MJ Fray et al. Discovery of potent and selective succinyl hydroxamate inhibitors of matrix metalloprotease-3 (Stromelysin-1). Bioorg. Med. Chem. Lett. 2001, 11(4), 571-574. MJ Fray et al. A potent, selective inhibitor of matrix metalloproteinase-3 for the topical treatment of chronic dermal ulcers. J. Med Chem. 2003, 46(16), 3514-3525. Certificate of Analysis Material Safety Data Sheet Angiogenesis Cell Signaling & Oncology Miscellaneous Pain & Inflammation EC 3.4.24.17 MMP Pfizer Licensed Products Potent MMP-3 (aka Stromelysin-1) inhibitor Chemical name (R)-N1-((S)-3,3-dimethyl-1-oxo-1-((R)-1-phenylethylamino)butan-2-yl)-N4-hydroxy-2-(3-(2-methylbiphenyl-4-yl)propyl)succinamide Source information Pfizer compound; Sold for research purposes under agreement from Pfizer Inc. Parent CAS No. [230961-08-7] Order Size Unit Price Stock 5 mg €90.00 In Stock |
产品价格 | 现货询价,电话:010-67529703 |
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产品品牌 | axonmedchem |
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UK 356618 - PF 03890101Axon 2111 CAS [230961-08-7] MF C34H43N3O4
Description
Potent and selective matrix metalloprotease-3 (MMP-3 aka stromelysin-1) inhibitor (IC50=5.9 nM); >140-fold selective over MMP-1, MMP-2, MMP-9 and MMP-14
Potent MMP-3 (aka Stromelysin-1) inhibitor
Chemical name(R)-N1-((S)-3,3-dimethyl-1-oxo-1-((R)-1-phenylethylamino)butan-2-yl)-N4-hydroxy-2-(3-(2-methylbiphenyl-4-yl)propyl)succinamide Source informationPfizer compound; Sold for research purposes under agreement from Pfizer Inc.Parent CAS No.[230961-08-7] |
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