产品名称

HL 010183

产品货号

Axon 2021 CAS [1429218-03-0] MF C14H20N6.HClMW 308.81 Purity: 99% Soluble in DMSO Description A metformin derivative exerting a potent anti-tumor effect; HL010183 inhibits proliferation and invasion of Hs578T triple-negative (TN) breast cancer cells; 100 fold more potent than metformin. KEYWORDS: HL 010183 | supplier | Antitumor agent | HL010183 | HL-010183 | CAS [1429218-03-0] | [1125365-14-1] | Glucose | Homeostasis | AMPK | metformin | anti-tumor | proliferation | Hs578T | breast cancer

产品价格

现货询价，电话：010-67529703

产品规格

产品品牌

axonmedchem

产品概述

产品详情

HL 010183

Based on 16 reference(s) in Google Scholar 9 10 16

Axon 2021

CAS [1429218-03-0]

MF C14H20N6.HCl
MW 308.81

Purity: 99%
Soluble in DMSO

HL 010183

Description

A metformin derivative exerting a potent anti-tumor effect; HL010183 inhibits proliferation and invasion of Hs578T triple-negative (TN) breast cancer cells; 100 fold more potent than metformin.

KEYWORDS: HL 010183 | supplier | Antitumor agent | HL010183 | HL-010183 | CAS [1429218-03-0] | [1125365-14-1] | Glucose | Homeostasis | AMPK | metformin | anti-tumor | proliferation | Hs578T | breast cancer

M Koh et al. A novel metformin derivative, HL010183, inhibits proliferation and invasion of triple-negative breast cancer cells. Bioorg. Med. Chem. 2013, 21(8), 2305-2313.

Cell Signaling & Oncology Diabetes & Metabolism Stem Cell AMPK PI3K-Akt-mTOR EC 2.7.11.31

Metformin derivative; AMPK activator

Chemical name

N2,N2-dimethyl-N4-(2-propylphenyl)-1,3,5-triazine-2,4,6-triamine hydrochloride

Parent CAS No.

[1125365-14-1]

产品资料