产品名称

A 769662

产品货号

Axon 1466 CAS [844499-71-4] MF C20H12N2O3SMW 360.39 Purity: 99% Soluble in DMSO Description Potent and selective activator of AMP-activated protein kinase (AMPK) β1 subunit-containing complexes References Certificates Categories Extra info B Cool et al. Identification and characterization of a small molecule AMPK activator that treats key components of type 2 diabetes and the metabolic syndrome. Cell Metabolism. 2006, 3, 403. M Sanders et al. Defining the mechanism of activation of AMP-activated protein kinase by the small molecule A-769662, a member of the thienopyridone family. J. Biol. Chem. 2007, 282, 32539. O Göransson et al. Mechanism of Action of A-769662, a Valuable Tool for Activation of AMP-activated Protein Kinase. J. Biol. Chem. 2007, 282, 32549-32560. JW Scott et al. Thienopyridone drugs are selective activators of AMP-activated protein kinase β1-containing complexes. Chem. Biol. 2008, 15, 1220. JT Treebak et al. A-769662 activates AMPK β1-containing complexes but induces glucose uptake through a PI3 kinase-dependent pathway in mouse skeletal muscle. Am. J. Physiol. Cell Physiol. 2009, 297(4), C1041-C1052. Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology Diabetes & Metabolism Stem Cell AMPK PI3K-Akt-mTOR EC 2.7.11.31 AMPK activator Chemical name 6,7-Dihydro-4-hydroxy-3-(2'-hydroxy[1,1'-biphenyl]-4-yl )-6-oxo-thieno[2,3-b]pyridine-5-carbonitrile Parent CAS No. [844499-71-4] Order Size Unit Price Stock 5 mg €85.00 In Stock

产品价格

现货询价，电话：010-67529703

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产品品牌

axonmedchem

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