产品名称

BAM15

产品货号

Axon 2736 CAS [210302-17-3] MF C16H10F2N6OMW 340.29 Purity: 99% Soluble in DMSO Description BAM15 is a mitochondrial protonophore uncoupler, which does not depolarize the plasma membrane. Compared to FCCP, an uncoupler of equal potency, BAM15 treatment of cultured cells stimulates a higher maximum rate of mitochondrial respiration and is less cytotoxic. Furthermore, BAM15 is bioactive in vivo and dose-dependently protects mice from acute renal ischemic-reperfusion injury. KEYWORDS: BAM15 | supplier | Mitochondrial uncoupler | BAM 15 | BAM-15 | CAS [210302-17-3] | Proton | Ionophore (proton) | Ionophore | Unclassified

产品价格

现货询价，电话：010-67529703

产品规格

产品品牌

axonmedchem

产品概述

产品详情

BAM15

Based on 5 reference(s) in Google Scholar 8 10 5

Axon 2736

CAS [210302-17-3]

MF C16H10F2N6O
MW 340.29

Purity: 99%
Soluble in DMSO

BAM15

Description

BAM15 is a mitochondrial protonophore uncoupler, which does not depolarize the plasma membrane. Compared to FCCP, an uncoupler of equal potency, BAM15 treatment of cultured cells stimulates a higher maximum rate of mitochondrial respiration and is less cytotoxic. Furthermore, BAM15 is bioactive in vivo and dose-dependently protects mice from acute renal ischemic-reperfusion injury.

B Kenwood et al. Identification of a novel mitochondrial uncoupler that does not depolarize the plasma membrane. Mol Metab. 2013 Nov 28;3(2):114-23.

Miscellaneous Ionophore

Mitochondrial protonophore uncoupler

Chemical name

N5,N6-Bis(2-fluorophenyl)-[1,2,5]oxadiazolo[3,4-b]pyrazine-5,6-diamine

Parent CAS No.

[210302-17-3]

产品资料