产品名称 Estetrol
产品货号 Axon 1926 CAS [15183-37-6] MF C18H24O4MW 304.38 Purity: 100% Optical purity: Optically pure Soluble in DMSO Description Estetrol has a relatively moderate affinity for human estrogen α receptor (ERα) and estrogen β receptor (ERβ), with Ki values of 4.9 nmol/l and 19 nmol/l, respectively. Nevertheless, at a concentration of 10 μmol/l, Estetrol shows nearly no affinity for a wide range of >120 other receptors, among them the glucocorticoid, progesterone and testosterone receptors. An estrogen steroid and a metabolite of Estradiol References Certificates Categories Extra info Estetrol review: profile and potential clinical applications. HJT Coelingh Bennink et al. Climacteric 2008, 11(Suppl 1), 47-58.  Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology Endocrinology Estrogen (ER) NR3A Estrogen receptor agonist, (four- to five-fold preference for the Erα) Chemical name (8R,9S,13S,14S,15R,16R,17R)-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-3,15,16,17-tetraol Parent CAS No. [15183-37-6] Order Size Unit Price Stock 5 mg €95.00 In Stock
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Estetrol

Based on 14 reference(s) in Google Scholar 8 10 14

Axon 1926

CAS [15183-37-6]

MF C18H24O4
MW 304.38

  • Purity: 100%
  • Optical purity: Optically pure
  • Soluble in DMSO

Estetrol

Description

Estetrol has a relatively moderate affinity for human estrogen α receptor (ERα) and estrogen β receptor (ERβ), with Ki values of 4.9 nmol/l and 19 nmol/l, respectively. Nevertheless, at a concentration of 10 μmol/l, Estetrol shows nearly no affinity for a wide range of >120 other receptors, among them the glucocorticoid, progesterone and testosterone receptors. An estrogen steroid and a metabolite of Estradiol
Estrogen receptor agonist, (four- to five-fold preference for the Erα)

Chemical name

(8R,9S,13S,14S,15R,16R,17R)-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-3,15,16,17-tetraol

Parent CAS No.

[15183-37-6]

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