产品名称

PPT

产品货号

Axon 1231 CAS [263717-53-9] MF C24H22N2O3MW 386.44 Purity: 99% Soluble in DMSO Description Specific estrogen receptor α (ERα) agonist. PPT significantly decreased infarct size in an in vivo rabbit model of ischemia-reperfusion injury. KEYWORDS: PPT | supplier | ER-α agonist | ER-alpha | Estrogen | CAS [263717-53-9] | Receptor | nuclear | NR3 | ischemia | reperfusion | infarct | cardiac | gene | transrepression | transactivation

产品价格

现货询价，电话：010-67529703

产品规格

产品品牌

axonmedchem

产品概述

产品详情

PPT

Based on 14 reference(s) in Google Scholar 8 10 14

Axon 1231

CAS [263717-53-9]

MF C24H22N2O3
MW 386.44

Purity: 99%
Soluble in DMSO

PPT

Description

Specific estrogen receptor α (ERα) agonist. PPT significantly decreased infarct size in an in vivo rabbit model of ischemia-reperfusion injury.

KEYWORDS: PPT | supplier | ER-α agonist | ER-alpha | Estrogen | CAS [263717-53-9] | Receptor | nuclear | NR3 | ischemia | reperfusion | infarct | cardiac | gene | transrepression | transactivation

Harris et al. Characterization of the biological roles of the estrogen receptors, ERα and ERβ, in estrogen target tissues in vivo through the use of an ERα-selective ligand. Endocrinology 2002, 143, 4172.

EA Booth et al. Activation of estrogen receptor-alpha protects the in vivo rabbit heart from ischemia-reperfusion injury. Am J Physiol Heart Circ Physiol. 2005 Nov;289(5):H2039-47.

WR Harrington et al. Activities of estrogen receptor alpha- and beta-selective ligands at diverse estrogen responsive gene sites mediating transactivation or transrepression. Mol Cell Endocrinol. 2003 Aug 29;206(1-2):13-22.

Cell Signaling & Oncology Endocrinology Estrogen (ER) NR3A

ER-α agonist

Chemical name

1,3,5-Tri-(4'-hydroxyphenyl)-4-propyl-1H-pyrazole

Parent CAS No.

[263717-53-9]

产品资料