产品名称

Irestatin 9389

产品货号

Axon 1656 CAS [626221-47-4] MF C16H13F3N4OS2MW 398.43 Purity: 99% Soluble in DMSO Description A potent inhibitor of the endonuclease IRE1 (IC50 = 6.3 nM) and unfolded protein response (UPR) References Certificates Categories Extra info D Feldman and AC Koong. Irestatin, a potent inhibitor of IRE1α and the unfolded protein response, is a hypoxia-selective cytotoxin and impairs tumor growth. J. Clin. Oncol. (2007 ASCO Ann. Meeting Proc. PI) 2007, 25 (18S), 3514. Certificate of Analysis Material Safety Data Sheet Apoptosis Cell Signaling & Oncology EC 2.7.11.1 IRE Endonuclease IRE1 inhibitor; UPR inhibitor Chemical name 2-(3-cyano-4-(trifluoromethyl)-6,7-dihydro-5H-cyclopenta[b]pyridin-2-ylthio)-N-(4-methylthiazol-2-yl)acetamide Parent CAS No. [626221-47-4] Order Size Unit Price Stock 10 mg €125.00 In Stock

产品价格

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产品规格

产品品牌

axonmedchem

产品概述

产品详情

Irestatin 9389

Based on 15 reference(s) in Google Scholar 8 10 15

Axon 1656

CAS [626221-47-4]

MF C16H13F3N4OS2
MW 398.43

Purity: 99%
Soluble in DMSO

Irestatin 9389

Description

A potent inhibitor of the endonuclease IRE1 (IC50 = 6.3 nM) and unfolded protein response (UPR)

D Feldman and AC Koong. Irestatin, a potent inhibitor of IRE1α and the unfolded protein response, is a hypoxia-selective cytotoxin and impairs tumor growth. J. Clin. Oncol. (2007 ASCO Ann. Meeting Proc. PI) 2007, 25 (18S), 3514.

IRE1 inhibitor; UPR inhibitor

Chemical name

2-(3-cyano-4-(trifluoromethyl)-6,7-dihydro-5H-cyclopenta[b]pyridin-2-ylthio)-N-(4-methylthiazol-2-yl)acetamide

Parent CAS No.

[626221-47-4]

产品资料