产品名称

VU 0361737

产品货号

Axon 1842 CAS [1161205-04-4] MF C13H11ClN2O2MW 262.69 Purity: 99% Soluble in DMSO Description Centrally penetrant and selective positive allosteric modulator (PAM) of metabotropic glutamate receptor subtype 4 (mGluR4); displayed submicromolar potency at both human and rat mGluR4 References Certificates Categories Extra info DW Engers et al. Synthesis and evaluation of a series of heterobiarylamides that are centrally penetrant metabotropic glutamate receptor 4 (mGluR4) positive allosteric modulators (PAMs). J. Med. Chem. 2009, 52(14), 4115-4118. DW Engers et al. Discovery, synthesis, and structure-activity relationship development of a series of N-(4-Acetamido)phenylpicolinamides as positive allosteric modulators of metabotropic glutamate receptor 4 (...). J. Med. Chem. 2011, 54(4), 1106-1110. Certificate of Analysis Material Safety Data Sheet CNS Pain & Inflammation mGluR4 C3 Positive allosteric modulator (PAM) of mGluR4 Chemical name N-(4-chloro-3-methoxyphenyl)picolinamide Parent CAS No. [1161205-04-4] Order Size Unit Price Stock 10 mg €85.00 In Stock

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现货询价，电话：010-67529703

产品规格

产品品牌

axonmedchem

产品概述

产品详情

VU 0361737

Based on 16 reference(s) in Google Scholar 9 10 16

Axon 1842

CAS [1161205-04-4]

MF C13H11ClN2O2
MW 262.69

Purity: 99%
Soluble in DMSO

VU 0361737

Description

Centrally penetrant and selective positive allosteric modulator (PAM) of metabotropic glutamate receptor subtype 4 (mGluR4); displayed submicromolar potency at both human and rat mGluR4

DW Engers et al. Synthesis and evaluation of a series of heterobiarylamides that are centrally penetrant metabotropic glutamate receptor 4 (mGluR4) positive allosteric modulators (PAMs). J. Med. Chem. 2009, 52(14), 4115-4118.

DW Engers et al. Discovery, synthesis, and structure-activity relationship development of a series of N-(4-Acetamido)phenylpicolinamides as positive allosteric modulators of metabotropic glutamate receptor 4 (...). J. Med. Chem. 2011, 54(4), 1106-1110.

Positive allosteric modulator (PAM) of mGluR4

Chemical name

N-(4-chloro-3-methoxyphenyl)picolinamide

Parent CAS No.

[1161205-04-4]

产品资料