产品名称 REP 8839
产品货号 Axon 1704 CAS [757942-43-1] MF C20H21BrFN3OSMW 450.37 Purity: 99% Soluble in DMSO Description Selective inhibitor of methionyl-tRNA synthetase (MetRS) with antibacterial activity against a variety of gram-positive organisms; Antibiotic References Certificates Categories Extra info LS Green et al. Inhibition of Methionyl-tRNA Synthetase by REP8839 and Effects of Resistance Mutations on Enzyme Activity. Antimicrob. Agents Chemother. 2009, 86–94.   IA Critchley et al. Antibacterial Activity of REP8839, a New Antibiotic for Topical Use. Antimicrob. Agents Chemother. 2005, 49(10), 4247–4252.   UA Ochsner et al. Mode of Action and Biochemical Characterization of REP8839, a Novel Inhibitor of Methionyl-tRNA Synthetase. Antimicrob Agents Chemother. 2005, 49(10), 4253–4262.   IA Critchley and UA Ochsner. Recent advances in the preclinical evaluation of the topical antibacterial agent REP8839. Curr. Opin. Chem. Biol. 2008, 12(4), 409-417.  Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology Immunology MetRS EC 6.1.1.10 Antibiotics MetRS inhibitor Chemical name 2-(3-((4-bromo-5-(1-fluorovinyl)-3-methylthiophen-2-yl)methylamino)propylamino)quinolin-4(1H)-one Parent CAS No. [757942-43-1] Order Size Unit Price Stock 10 mg €125.00 In Stock
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