产品名称 JIB 04 - NSC 693627
产品货号 Axon 2160 CAS [199596-05-9] MF C17H13ClN4MW 308.76 Purity: 99% Soluble in 0.1N HCl(aq) and DMSO Description Potent, cell permeable and selective Jumonji histone demethylase inhibitor in vitro and in vivo; JIB-04 is not a competitive inhibitor of α-ketoglutarate and it modulates transcription in cancer-selective manner References Certificates Categories Extra info L Wang et al. A small molecule modulates Jumonji histone demethylase activity and selectively inhibits cancer growth. Nat. Commun. 2013, 4, 2035.  Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology Epigenetics EC 1.14.11 Histone demethylase Antibiotics Jumonji histone demethylase inhibitor Chemical name (E)-5-chloro-2-(2-(phenyl(pyridin-2-yl)methylene)hydrazinyl)pyridine Parent CAS No. [199596-05-9] Order Size Unit Price Stock 10 mg €90.00 In Stock
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JIB 04 - NSC 693627

Based on 16 reference(s) in Google Scholar 9 10 16

Axon 2160

CAS [199596-05-9]

MF C17H13ClN4
MW 308.76

  • Purity: 99%
  • Soluble in 0.1N HCl(aq) and DMSO

JIB 04

Description

Potent, cell permeable and selective Jumonji histone demethylase inhibitor in vitro and in vivo; JIB-04 is not a competitive inhibitor of α-ketoglutarate and it modulates transcription in cancer-selective manner
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