| 产品名称 | ABT 102 |
| 产品货号 | Axon 1504 CAS [808756-71-0] MF C21H24N4OMW 348.44 Purity: 99% Optical purity: Optically pure Soluble in DMSO Description Potent and selective antagonist of transient receptor potential vanilloid 1 (TRPV1) receptors (IC50 values to be 5-7 nM) under clinical trials; TRVP1 receptor antagonism is a promising approach for pain management References Certificates Categories Extra info CS Surowy et al. ABT-102 Blocks Polymodal Activation of Transient Receptor Potential Vanilloid 1 Receptors in Vitro and Heat-Evoked Firing of Spinal Dorsal Horn Neurons in Vivo. JPET 2008, 326(3), 879-888. P Honore et al. Repeated dosing of ABT-102, a potent and selective TRPV1 antagonist, enhances TRPV1-mediated analgesic activity in rodents, but attenuates antagonist-induced hyperthermia. Pain. 2009, 142(1-2), 27-35. Certificate of Analysis Material Safety Data Sheet CNS Pain & Inflammation TRPV1 Unclassified TRPV1 antagonist Chemical name (R)-1-(5-tert-Butyl-2,3-dihydro-1H-inden-1-yl)-3-(1H-indazol-4-yl)urea Parent CAS No. [808756-71-0] Order Size Unit Price Stock 5 mg €90.00 In Stock |
| 产品价格 | 现货询价，电话：010-67529703 |
| 产品规格 | |
| 产品品牌 | axonmedchem |
| 产品概述 | |
| 产品详情 |
ABT 102Axon 1504 CAS [808756-71-0] MF C21H24N4O
Description
Potent and selective antagonist of transient receptor potential vanilloid 1 (TRPV1) receptors (IC50 values to be 5-7 nM) under clinical trials; TRVP1 receptor antagonism is a promising approach for pain management
TRPV1 antagonist
Chemical name(R)-1-(5-tert-Butyl-2,3-dihydro-1H-inden-1-yl)-3-(1H-indazol-4-yl)urea Parent CAS No.[808756-71-0] |
| 产品资料 |
