产品名称 HIF-2a Translation Inhibitor 76
产品货号 Axon 2614 CAS [882268-69-1] MF C9H9N3O4S2MW 287.32 Purity: 99% Soluble in DMSO Description HIF-2a translation inhibitor (IC50 value 5 µM); Decreases HIF-2a protein and HIF-2a target gene expression in normoxia and hypoxia independent of HIF-2a mRNA expression or HIF-2a protein stability, and independent of mTOR activity. Moreover, the translation inhibitor 76 enhances binding of IRP1 to the HIF-2a IRE (Iron-Responsive Element). KEYWORDS: HIF-2a Translation Inhibitor 76 | supplier | HIF2a translation inhibitor | CAS [882268-69-1] | DNA-RNA | HIF-2α | Transcription Factor | Iron-Responsive Element | IRE | mTOR | hypoxia | IRP1
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HIF-2a Translation Inhibitor 76

Based on 2 reference(s) in Google Scholar 9 10 2

Axon 2614

CAS [882268-69-1]

MF C9H9N3O4S2
MW 287.32

  • Purity: 99%
  • Soluble in DMSO

HIF-2a Translation Inhibitor 76

Description

HIF-2a translation inhibitor (IC50 value 5 µM); Decreases HIF-2a protein and HIF-2a target gene expression in normoxia and hypoxia independent of HIF-2a mRNA expression or HIF-2a protein stability, and independent of mTOR activity. Moreover, the translation inhibitor 76 enhances binding of IRP1 to the HIF-2a IRE (Iron-Responsive Element).

KEYWORDS: HIF-2a Translation Inhibitor 76 | supplier | HIF2a translation inhibitor | CAS [882268-69-1] | DNA-RNA | HIF-2α | Transcription Factor | Iron-Responsive Element | IRE | mTOR | hypoxia | IRP1

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