产品名称 HIF-2 inhibitor 2 - Compound 2
产品货号 Axon 2034 CAS [1422955-31-4] MF C12H6ClFN4O3MW 308.65 Purity: 100% Soluble in DMSO Description Allosteric inhibitor of HIF-2, which selectively antagonizes HIF-2 heterodimerization and DNA-binding activity in vitro and in cultured cells, reducing HIF-2 target gene expression References Certificates Categories Extra info TH Scheuermann et al. Allosteric inhibition of hypoxia inducible factor-2 with small molecules. Nat. Chem. Biol. 2013, 9, 271–276.  Certificate of Analysis Material Safety Data Sheet Angiogenesis Cell Signaling & Oncology Epigenetics Transcription Factors TF class 1.2 HIF Allosteric inhibitor of HIF-2 Chemical name N-(3-chloro-5-fluorophenyl)-4-nitrobenzo[c][1,2,5]oxadiazol-5-amine Parent CAS No. [1422955-31-4] Order Size Unit Price Stock 5 mg €95.00 In Stock
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HIF-2 inhibitor 2 - Compound 2

Based on 12 reference(s) in Google Scholar 9 10 12

Axon 2034

CAS [1422955-31-4]

MF C12H6ClFN4O3
MW 308.65

  • Purity: 100%
  • Soluble in DMSO

HIF-2 inhibitor 2

Description

Allosteric inhibitor of HIF-2, which selectively antagonizes HIF-2 heterodimerization and DNA-binding activity in vitro and in cultured cells, reducing HIF-2 target gene expression
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