产品名称 IOX2
产品货号 Axon 1921 CAS [931398-72-0] MF C19H16N2O5MW 352.34 Purity: 100% Soluble in DMSO Description A selective inhibitor of the Hypoxia Inducible Factor (HIF) Prolyl-Hydroxylases (PHD); active in cells with IC50 value of 21 nM for PHD2/ELGN-1 and no inhibition at FIH (20µM) References Certificates Categories Extra info YM Tian et al. Differential sensitivity of hypoxia inducible factor hydroxylation sites to hypoxia and hydroxylase inhibitors. J. Biol. Chem. 2011, 286(15), 13041-13051.   JK Murray et al. Dipeptidyl-quinolone derivatives inhibit hypoxia inducible factor-1α prolyl hydroxylases-1, -2, and -3 with altered selectivity. J. Comb. Chem. 2010, 12(5), 676-686. Certificate of Analysis Material Safety Data Sheet Angiogenesis Cell Signaling & Oncology Epigenetics PHD (HIF) Transcription Factors EC 1.14.11.29 Inhibitor of Hypoxia Inducible Factor PHD Chemical name 2-(1-benzyl-4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carboxamido)acetic acid Parent CAS No. [931398-72-0] Order Size Unit Price Stock 5 mg €95.00 In Stock
产品价格 现货询价,电话:010-67529703
产品规格
产品品牌 axonmedchem
产品概述
产品详情

IOX2

Based on 16 reference(s) in Google Scholar 9 10 16

Axon 1921

CAS [931398-72-0]

MF C19H16N2O5
MW 352.34

  • Purity: 100%
  • Soluble in DMSO

IOX2

Description

A selective inhibitor of the Hypoxia Inducible Factor (HIF) Prolyl-Hydroxylases (PHD); active in cells with IC50 value of 21 nM for PHD2/ELGN-1 and no inhibition at FIH (20µM)
产品资料