产品名称 | 10058-F4 |
产品货号 | Axon 2222 CAS [403811-55-2] MF C12H11NOS2MW 249.35 Purity: 99% Soluble in 0.1N NaOH(aq) and DMSO Description Small-molecule c-Myc inhibitor that induces cell-cycle arrest at G0/G1 phase in a dose-dependent manner. 10058-F4 targets c-Myc-Max, to disrupt the heterodimer and/or to prevent its formation, and abrogates various c-Myc–dependent functions, and induces myeloid differentiation of human acute myeloid leukemia. References Certificates Categories Extra info M.J. Huang et al. A small-molecule c-Myc inhibitor, 10058-F4, induces cell-cycle arrest, apoptosis, and myeloid differentiation of human acute myeloid leukemia. Exp. Hematol. 2006, 34, 1480-1489. H. Wang et al. Improved low molecular weight Myc-Max inhibitors. Mol. Cancer Ther. 2007, 6, 2399-2408. Certificate of Analysis Material Safety Data Sheet Apoptosis Cell Cycle Regulation Cell Signaling & Oncology c-MYC Transcription Factors TF class 1.3.2 Stem Cell Differentiator c-Myc inhibitor inducing cell-cycle arrest at G0/G1 phase Chemical name 5-(4-ethylbenzylidene)-2-thioxothiazolidin-4-one Parent CAS No. [403811-55-2] Order Size Unit Price Stock 10 mg €80.00 In Stock |
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产品品牌 | axonmedchem |
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10058-F4Axon 2222 CAS [403811-55-2] MF C12H11NOS2
Description
Small-molecule c-Myc inhibitor that induces cell-cycle arrest at G0/G1 phase in a dose-dependent manner. 10058-F4 targets c-Myc-Max, to disrupt the heterodimer and/or to prevent its formation, and abrogates various c-Myc–dependent functions, and induces myeloid differentiation of human acute myeloid leukemia.
c-Myc inhibitor inducing cell-cycle arrest at G0/G1 phase
Chemical name5-(4-ethylbenzylidene)-2-thioxothiazolidin-4-one Parent CAS No.[403811-55-2] |
产品资料 |