| 产品名称 | Optovin |
| 产品货号 | Axon 2374 CAS [348575-88-2] MF C15H13N3OS2MW 315.41 Purity: 99% Soluble in 0.1N NaOH(aq) and DMSO Description Reversible photoactivated TRPA1 agonist (EC50 value 2 μM) that specifically activates TRPA1, but not TRPV1 or TRPM8. Optovin activates human TRPA1 via structure-dependent photochemical reactions with redox-sensitive cysteine residues, and enables control of motor activity in paralyzed extremities by localized illumination in animals. Optovin-treated animals respond to 387-nm (violet) stimuli but not to 485-nm (blue), 560-nm (green) or longer wavelengths. References Certificates Categories Extra info O. Fajardo et al. Optopharmacology: a light switch for pain. Nat Chem Biol. 2013 Apr;9(4):219-20. D. Kokel et al. Photochemical activation of TRPA1 channels in neurons and animals. Nat Chem Biol. 2013 Apr;9(4):257-63. Certificate of Analysis Material Safety Data Sheet CNS Pain & Inflammation Unclassified TRPA1 Reversible photoactivated TRPA1 agonist Chemical name 5-((2,5-dimethyl-1-(pyridin-3-yl)-1H-pyrrol-3-yl)methylene)-2-thioxothiazolidin-4-one Parent CAS No. [348575-88-2] Order Size Unit Price Stock 5 mg €85.00 In Stock |
| 产品价格 | 现货询价，电话：010-67529703 |
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| 产品品牌 | axonmedchem |
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| 产品详情 |
OptovinAxon 2374 CAS [348575-88-2] MF C15H13N3OS2
Description
Reversible photoactivated TRPA1 agonist (EC50 value 2 μM) that specifically activates TRPA1, but not TRPV1 or TRPM8. Optovin activates human TRPA1 via structure-dependent photochemical reactions with redox-sensitive cysteine residues, and enables control of motor activity in paralyzed extremities by localized illumination in animals. Optovin-treated animals respond to 387-nm (violet) stimuli but not to 485-nm (blue), 560-nm (green) or longer wavelengths.
Reversible photoactivated TRPA1 agonist
Chemical name5-((2,5-dimethyl-1-(pyridin-3-yl)-1H-pyrrol-3-yl)methylene)-2-thioxothiazolidin-4-one Parent CAS No.[348575-88-2] |
| 产品资料 |
