产品名称

HTI 286 - SPA 110 | Taltobulin

产品货号

Axon 1650 CAS [228266-40-8] MF C27H43N3O4MW 473.65 Purity: 99% Optical purity: Optically pure Soluble in DMSO Description Potent tubulin inhibitor; a synthetic hemiasterlin analogue, which is a potent inhibitor of cell growth with an additional advantage of circumventing the P-glycoprotein-mediated resistance References Certificates Categories Extra info F Loganzo et al. HTI-286, a Synthetic Analogue of the Tripeptide Hemiasterlin, Is a Potent Antimicrotubule Agent that Circumvents P-Glycoprotein-mediated Resistance in Vitro and in Vivo. Cancer Res. 2003, 63, 1838. C Redaelli et al. Synthetic tubulin inhibitor HTI-286 and hepatocellular carcinoma: an in-vitro and and in-vivo study. J. Clin. Oncol. (Meeting Abstracts) 2005, 23(16S), 4201. BA Hadaschik et al. Targeting prostate cancer with HTI-286, a synthetic analog of the marine sponge product hemiasterlin. Int. J. Cancer. 2008, 122(10), 2368-2376. Y Matsui et al. Intravesical combination treatment with antisense oligonucleotides targeting heat shock protein-27 and HTI-286 as a novel strategy for high-grade bladder cancer. Mol. Cancer Ther. 2009, 8(8), 2402-2411. Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology Tubulin Globular Proteins Tubulin polymerization inhibitor Chemical name (S,E)-2,5-dimethyl-4-((S)-N,3,3-trimethyl-2-((S)-3-methyl-2-(methylamino)-3-phenylbutanamido)butanamido)hex-2-enoic acid Parent CAS No. [228266-40-8] Order Size Unit Price Stock 5 mg €125.00 In Stock

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产品规格

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axonmedchem

产品概述

产品详情

HTI 286 - SPA 110 | Taltobulin

Based on 12 reference(s) in Google Scholar 9 10 12

Axon 1650

CAS [228266-40-8]

MF C27H43N3O4
MW 473.65

Purity: 99%
Optical purity: Optically pure
Soluble in DMSO

HTI 286

Description

Potent tubulin inhibitor; a synthetic hemiasterlin analogue, which is a potent inhibitor of cell growth with an additional advantage of circumventing the P-glycoprotein-mediated resistance

F Loganzo et al. HTI-286, a Synthetic Analogue of the Tripeptide Hemiasterlin, Is a Potent Antimicrotubule Agent that Circumvents P-Glycoprotein-mediated Resistance in Vitro and in Vivo. Cancer Res. 2003, 63, 1838.

C Redaelli et al. Synthetic tubulin inhibitor HTI-286 and hepatocellular carcinoma: an in-vitro and and in-vivo study. J. Clin. Oncol. (Meeting Abstracts) 2005, 23(16S), 4201.

BA Hadaschik et al. Targeting prostate cancer with HTI-286, a synthetic analog of the marine sponge product hemiasterlin. Int. J. Cancer. 2008, 122(10), 2368-2376.

Y Matsui et al. Intravesical combination treatment with antisense oligonucleotides targeting heat shock protein-27 and HTI-286 as a novel strategy for high-grade bladder cancer. Mol. Cancer Ther. 2009, 8(8), 2402-2411.

Cell Signaling & Oncology Tubulin Globular Proteins

Tubulin polymerization inhibitor

Chemical name

(S,E)-2,5-dimethyl-4-((S)-N,3,3-trimethyl-2-((S)-3-methyl-2-(methylamino)-3-phenylbutanamido)butanamido)hex-2-enoic acid

Parent CAS No.

[228266-40-8]

产品资料