产品名称 | AZ 23 |
产品货号 | Axon 1610 CAS [915720-21-7] MF C17H19ClFN7OMW 391.83 Purity: 99% Optical purity: Optically pure Soluble in DMSO Description Potent and selective tyrosine kinase (Trk) inhibitor with IC50 to 2 and 8 nM for TrkA and TrkB respectively; AZ-23 showed in vivo TrkA kinase inhibition and efficacy in mice following oral administration; having potential for therapeutic utility in neuroblastoma and multiple other cancer indications. KEYWORDS: AZ 23 | supplier | TrkA inhibitor | AZ23 |CAS[915720-21-7] | Neurotrophin | Trk | Inhibitor | tyrosine kinase | TrkA | TrkB | neuroblastoma | cancer |
产品价格 | 现货询价,电话:010-67529703 |
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产品品牌 | axonmedchem |
产品概述 | |
产品详情 |
AZ 23Axon 1610 CAS [915720-21-7] MF C17H19ClFN7O
DescriptionPotent and selective tyrosine kinase (Trk) inhibitor with IC50 to 2 and 8 nM for TrkA and TrkB respectively; AZ-23 showed in vivo TrkA kinase inhibition and efficacy in mice following oral administration; having potential for therapeutic utility in neuroblastoma and multiple other cancer indications. KEYWORDS: AZ 23 | supplier | TrkA inhibitor | AZ23 |CAS[915720-21-7] | Neurotrophin | Trk | Inhibitor | tyrosine kinase | TrkA | TrkB | neuroblastoma | cancer
TrkA and TrkB inhibitor
Chemical name(S)-5-chloro-N2-(1-(5-fluoropyridin-2-yl)ethyl)-N4-(5-isopropoxy-1H-pyrazol-3-yl)pyrimidine-2,4-diamine Parent CAS No.[915720-21-7] |
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