| 产品名称 | PD 90780 |
| 产品货号 | Axon 2174 CAS [77422-99-2] MF C19H14N4O4MW 362.34 Purity: 99% Soluble in DMSO Description A nonpeptide inhibitor of nerve growth factor's binding to the P75 NGF receptor; It binds to NGF, not to the P75 receptor. Differential activity of PD90780 suggests altered NGF-p75NTR interactions in the presence of TrkA. References Certificates Categories Extra info K Spiegel et al. PD 90780, a nonpeptide inhibitor of nerve growth factor's binding to the P75 NGF receptor. Biochem. Biophys. Res. Comm. 1995, 217, 488-494. A Colquhoun et al. Differential activity of the nerve growth factor (NGF) antagonist PD90780 [7-(benzolylamino)-4,9-dihydro-4-methyl-9-oxo-pyrazolo[5,1-b]quinazoline-2-carboxylic acid] suggests altered (...). J. Pharm. Exp. Ther. 2004, 310, 505-511. Certificate of Analysis Material Safety Data Sheet Apoptosis Cell Signaling & Oncology p75 NTR NF-κB MAPK JAK-STAT PI3K-Akt-mTOR RTK class VII; EC 2.7.10.1 Inhibitor of NGFs binding to the P75 NGFR Chemical name 7-benzamido-4-methyl-9-oxo-4,9-dihydropyrazolo[5,1-b]quinazoline-2-carboxylic acid Parent CAS No. [77422-99-2] Order Size Unit Price Stock 5 mg €95.00 In Stock |
| 产品价格 | 现货询价，电话：010-67529703 |
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| 产品品牌 | axonmedchem |
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PD 90780Axon 2174 CAS [77422-99-2] MF C19H14N4O4
Description
A nonpeptide inhibitor of nerve growth factor's binding to the P75 NGF receptor; It binds to NGF, not to the P75 receptor. Differential activity of PD90780 suggests altered NGF-p75NTR interactions in the presence of TrkA.
Inhibitor of NGFs binding to the P75 NGFR
Chemical name7-benzamido-4-methyl-9-oxo-4,9-dihydropyrazolo[5,1-b]quinazoline-2-carboxylic acid Parent CAS No.[77422-99-2] |
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