产品名称

Dihydroxyflavone, 7,8- - DHF, 7,8-

产品货号

Axon 2089 CAS [38183-03-8] MF C15H10O4MW 254.24 Purity: 99% Soluble in DMSO and Ethanol Description Potent and selective tyrosine kinase receptor B (TrkB) agonist. 7,8-Dihydroxyflavone imitates Brain-derived neurotrophic factor (BDNF) and acts as a robust TrkB agonist, providing a powerful therapeutic tool for the treatment of various neurological diseases References Certificates Categories Extra info SW Jang et al. A selective TrkB agonist with potent neurotrophic activities by 7,8-dihydroxyflavone. Proc. Natl. Acad. Sci. USA 2010, 107, 2687-2692. R Andero et al. Effect of 7, 8-dihydroxyflavone, a small-molecule TrkB agonist, on emotional learning. Am. J. Psychiatry 2011, 168(2), 163-172. L Devi & M Ohno. 7, 8-dihydroxyflavone, a small-molecule TrkB agonist, reverses memory deficits and BACE1 elevation in a mouse model of Alzheimer's disease. Neuropsychopharmacol. 2011, 37(2), 434-444. Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology RTK class VII; EC 2.7.10.1 Trk Tyrosine kinase receptor B (TrkB) agonist Chemical name 7,8-dihydroxy-2-phenyl-4H-chromen-4-one Parent CAS No. [38183-03-8] Order Size Unit Price Stock 10 mg €55.00 In Stock

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产品规格

产品品牌

axonmedchem

产品概述

产品详情

Dihydroxyflavone, 7,8- - DHF, 7,8-

Based on 14 reference(s) in Google Scholar 8 10 14

Axon 2089

CAS [38183-03-8]

MF C15H10O4
MW 254.24

Purity: 99%
Soluble in DMSO and Ethanol

Dihydroxyflavone, 7,8-

Description

Potent and selective tyrosine kinase receptor B (TrkB) agonist. 7,8-Dihydroxyflavone imitates Brain-derived neurotrophic factor (BDNF) and acts as a robust TrkB agonist, providing a powerful therapeutic tool for the treatment of various neurological diseases

SW Jang et al. A selective TrkB agonist with potent neurotrophic activities by 7,8-dihydroxyflavone. Proc. Natl. Acad. Sci. USA 2010, 107, 2687-2692.

R Andero et al. Effect of 7, 8-dihydroxyflavone, a small-molecule TrkB agonist, on emotional learning. Am. J. Psychiatry 2011, 168(2), 163-172.

L Devi & M Ohno. 7, 8-dihydroxyflavone, a small-molecule TrkB agonist, reverses memory deficits and BACE1 elevation in a mouse model of Alzheimer's disease. Neuropsychopharmacol. 2011, 37(2), 434-444.

Tyrosine kinase receptor B (TrkB) agonist

Chemical name

7,8-dihydroxy-2-phenyl-4H-chromen-4-one

Parent CAS No.

[38183-03-8]

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