产品名称 Reversine
产品货号 Axon 1629 CAS [656820-32-5] MF C21H27N7OMW 393.49 Purity: 99% Soluble in DMSO Description Reversine induces differentiated myogenic-lineage committed cells to become multipotent mesenchymal progenitor cells; it is a potent mitotic inhibitor of MPS1 kinase, which inhibits the spindle assembly checkpoint in a dose-dependent manner; also acts as A3 adenosine receptor antagonist (Ki: 660 nM) or aurora kinases inhibitor (IC50: 400-500 nM for Aurora A/B/C respectively). KEYWORDS: Reversine | supplier | MPS1 inhibitor | CAS [656820-32-5] | Non Selective (Mitotic Spindle Checkpoint) | MPS1 Kinase | Inhibitor | Enzymes
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产品品牌 axonmedchem
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Reversine

Based on 18 reference(s) in Google Scholar 9 10 18

Axon 1629

CAS [656820-32-5]

MF C21H27N7O
MW 393.49

  • Purity: 99%
  • Soluble in DMSO

Reversine

Description

Reversine induces differentiated myogenic-lineage committed cells to become multipotent mesenchymal progenitor cells; it is a potent mitotic inhibitor of MPS1 kinase, which inhibits the spindle assembly checkpoint in a dose-dependent manner; also acts as A3 adenosine receptor antagonist (Ki: 660 nM) or aurora kinases inhibitor (IC50: 400-500 nM for Aurora A/B/C respectively).

KEYWORDS: Reversine | supplier | MPS1 inhibitor | CAS [656820-32-5] | Non Selective (Mitotic Spindle Checkpoint) | MPS1 Kinase | Inhibitor | Enzymes

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