产品名称 | UK 432097 |
产品货号 | Axon 1193 CAS [380221-63-6] MF C40H47N11O6MW 777.87 Purity: 99% Soluble in 0.1N HCl(aq) and DMSO Description Potent and selective A2A-adenosine receptor agonist; agent developed by Pfizer for chronic obstructive pulmonary disease (category Allergy/Respiratory); its high selectivity has made it useful for detailed mapping of the internal structure of the A2A receptor. Expert recommendation - a highly recommended tool in research of A2A receptor. References Certificates Categories Extra info C. Russo et al. Adenosine receptors: promising targets for the development of novel therapeutics and diagnostics for asthma. Fundam. Clin. Pharmacol. 2006, 20, 9-19. Safety and efficacy of UK-432,097 in chronic obstructive pulmonary disease. ClinicalTrials.gov 2013. F. Xu et al. Structure of an Agonist-Bound Human A2A Adenosine Receptor. Science 2011, 332(6027), 322-327. (* UK 432097 used in this study was procured from Axon Medchem.) |
产品价格 | 现货询价,电话:010-67529703 |
产品规格 | |
产品品牌 | axonmedchem |
产品概述 | |
产品详情 |
UK 432097Axon 1193 CAS [380221-63-6] MF C40H47N11O6
DescriptionPotent and selective A2A-adenosine receptor agonist; agent developed by Pfizer for chronic obstructive pulmonary disease (category Allergy/Respiratory); its high selectivity has made it useful for detailed mapping of the internal structure of the A2A receptor. Expert recommendation - a highly recommended tool in research of A2A receptor. (* UK 432097 used in this study was procured from Axon Medchem.)
Adenosine A2A agonist
Chemical name6-[(2,2-Diphenylethyl)amino]-9-{(2R,3R,4S,5S)-5-[(ethylamino)carbonyl]-3,4-dihydroxytetrahydro-2-furanyl}-N-{2-[({[1-(2-pyridinyl)-4-piperidinyl]amino}carbonyl)amino]ethyl}-9H-purine-2-carboxamide Parent CAS No.[380221-63-6] |
产品资料 |