| 产品名称 | MLR 1023 - Tolimidone | CP 26154 |
| 产品货号 | Axon 1941 CAS [41964-07-2] MF C11H10N2O2MW 202.21 Purity: 99% Soluble in DMSO Description Selective allosteric activator of Lyn kinase (EC50: 63 nM); no significant activity against all other Src family kinases and a range of 47 other kinases; Next generation insulin sensitizer that does not have PPAR activity References Certificates Categories Extra info MS Saporito et al. MLR-1023 is a potent and selective allosteric activator of Lyn kinase in vitro that improves glucose tolerance in vivo. J. Pharmacol. Exp. Ther. 2012, 342(1), 15-22. AR Ochman et al. The Lyn kinase activator MLR-1023 is a novel insulin receptor potentiator that elicits a rapid-onset and durable improvement in glucose homeostasis in animal models of type 2 diabetes. J. Pharmacol. Exp. Ther. 2012, 342(1), 23-32. Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology Endocrinology SRC Lyn EC 2.7.10.2 Selective allosteric activator of Lyn kinase Chemical name 5-(m-tolyloxy)pyrimidin-2(1H)-one Parent CAS No. [41964-07-2] Order Size Unit Price Stock 10 mg €95.00 In Stock |
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| 产品品牌 | axonmedchem |
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MLR 1023 - Tolimidone | CP 26154Axon 1941 CAS [41964-07-2] MF C11H10N2O2
Description
Selective allosteric activator of Lyn kinase (EC50: 63 nM); no significant activity against all other Src family kinases and a range of 47 other kinases; Next generation insulin sensitizer that does not have PPAR activity
Selective allosteric activator of Lyn kinase
Chemical name5-(m-tolyloxy)pyrimidin-2(1H)-one Parent CAS No.[41964-07-2] |
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