产品名称

OC 000459

产品货号

Axon 1913 CAS [851723-84-7] MF C21H17FN2O2MW 348.37 Purity: 98% Soluble in 0.1N NaOH(aq) and DMSO Description Potent, oral and selective CRTH2 (also known as DP2) antagonist; under clinic development References Certificates Categories Extra info R Pettipher et al. Pharmacologic Profile of OC000459, a Potent, Selective, and Orally Active D Prostanoid Receptor 2 Antagonist That Inhibits Mast Cell-Dependent Activation of T Helper 2 (...). J. Pharmacol. Exp. Ther. 2012, 340(2), 473-482. F Horak et al. The CRTH2 antagonist OC000459 reduces nasal and ocular symptoms in allergic subjects exposed to grass pollen, a randomised, placebo-controlled, double-blind trial. Allergy 2012 Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology Pain & Inflammation CRTH2 A14 Selective DP2 (CRTH2) antagonist Chemical name 2-(5-fluoro-2-methyl-3-(quinolin-2-ylmethyl)-1H-indol-1-yl)acetic acid Parent CAS No. [851723-84-7] Order Size Unit Price Stock 5 mg €90.00 In Stock

产品价格

现货询价，电话：010-67529703

产品规格

产品品牌

axonmedchem

产品概述

产品详情

OC 000459

Based on 12 reference(s) in Google Scholar 9 10 12

Axon 1913

CAS [851723-84-7]

MF C21H17FN2O2
MW 348.37

Purity: 98%
Soluble in 0.1N NaOH(aq) and DMSO

OC 000459

Description

Potent, oral and selective CRTH2 (also known as DP2) antagonist; under clinic development

R Pettipher et al. Pharmacologic Profile of OC000459, a Potent, Selective, and Orally Active D Prostanoid Receptor 2 Antagonist That Inhibits Mast Cell-Dependent Activation of T Helper 2 (...). J. Pharmacol. Exp. Ther. 2012, 340(2), 473-482.

F Horak et al. The CRTH2 antagonist OC000459 reduces nasal and ocular symptoms in allergic subjects exposed to grass pollen, a randomised, placebo-controlled, double-blind trial. Allergy 2012

Selective DP2 (CRTH2) antagonist

Chemical name

2-(5-fluoro-2-methyl-3-(quinolin-2-ylmethyl)-1H-indol-1-yl)acetic acid

Parent CAS No.

[851723-84-7]

产品资料