产品名称 KY 02111
产品货号 Axon 2036 CAS [1118807-13-8] MF C18H17ClN2O3SMW 376.86 Purity: 98% Soluble in DMSO Description A canonical Wnt signaling pathway inhibitor that promotes differentiation of human pluripotent stem cells (hPSCs), including ESCs and iPSCs, to cardiomyocytes. KY02111 acts downstream of APC and GSK-3β to inhibit Wnt signaling; KY02111 and Wnt inhibitors, such as XAV 939 (Axon 1527), cooperatively enhance hPSC cardiomyogenesis; KY 02111 and WNT modulators, CHIR 99021 (Axon 1386) and/or BIO (Axon 1693) permit cytokine and xeno-free hPSC cardiomyogenesis References Certificates Categories Extra info I Minami et al. A Small Molecule that Promotes Cardiac Differentiation of Human Pluripotent Stem Cells under Defined, Cytokine- and Xeno-free Conditions. Cell Reports 2012, 2(5), 1448–1460.    W Li et al. Chemical approaches to studying stem cell biology. (review article). Cell Res. 2013, 23, 81–91.  Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology Stem Cell Wnt-β-Catenin Wnt Canonical Wnt signaling pathway inhibitor Chemical name N-(6-chlorobenzo[d]thiazol-2-yl)-3-(3,4-dimethoxyphenyl)propanamide Parent CAS No. [1118807-13-8] Order Size Unit Price Stock 10 mg €80.00 In Stock
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KY 02111

Based on 16 reference(s) in Google Scholar 9 10 16

Axon 2036

CAS [1118807-13-8]

MF C18H17ClN2O3S
MW 376.86

  • Purity: 98%
  • Soluble in DMSO

KY 02111

Description

A canonical Wnt signaling pathway inhibitor that promotes differentiation of human pluripotent stem cells (hPSCs), including ESCs and iPSCs, to cardiomyocytes. KY02111 acts downstream of APC and GSK-3β to inhibit Wnt signaling; KY02111 and Wnt inhibitors, such as XAV 939 (Axon 1527), cooperatively enhance hPSC cardiomyogenesis; KY 02111 and WNT modulators, CHIR 99021 (Axon 1386) and/or BIO (Axon 1693) permit cytokine and xeno-free hPSC cardiomyogenesis

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