产品名称

AZD 8330

产品货号

Axon 1999 CAS [869357-68-6] MF C16H17FIN3O4MW 461.23 Purity: 98% Soluble in DMSO Description Potent, highly specific non-ATP-competitive MEK inhibitor; AZD8330 specifically inhibits mitogen-activated protein kinase kinase 1 (MEK or MAP/ERK kinase1), resulting in inhibition of growth factor-mediated cell signaling and tumor cell proliferation References Certificates Categories Extra info JI Trujillo. MEK inhibitors: a patent review 2008-2010. Exp. Opin. Ther. Patents. 2011, 21(7), 1045-1069. MS Chapman & JN Miner. Novel mitogen-activated protein kinase kinase inhibitors. Exp. Opin. Invest. Drugs. 2011, 20(2), 209-220. C Frémin and S Meloche. From basic research to clinical development of MEK1/2 inhibitors for cancer therapy. J. Hematol. Oncol. 2010, 3, 8. Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology MAPK EC 2.7.12.2 MEK MEK 1 inhibitor Chemical name 2-(2-fluoro-4-iodophenylamino)-N-(2-hydroxyethoxy)-1,5-dimethyl-6-oxo-1,6-dihydropyridine-3-carboxamide Parent CAS No. [869357-68-6] Order Size Unit Price Stock 5 mg €105.00 In Stock

产品价格

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产品规格

产品品牌

axonmedchem

产品概述

产品详情

AZD 8330

Based on 18 reference(s) in Google Scholar 9 10 18

Axon 1999

CAS [869357-68-6]

MF C16H17FIN3O4
MW 461.23

Purity: 98%
Soluble in DMSO

AZD 8330

Description

Potent, highly specific non-ATP-competitive MEK inhibitor; AZD8330 specifically inhibits mitogen-activated protein kinase kinase 1 (MEK or MAP/ERK kinase1), resulting in inhibition of growth factor-mediated cell signaling and tumor cell proliferation