| 产品名称 | AIM 100 |
| 产品货号 | Axon 2031 CAS [873305-35-2] MF C23H21N3O2MW 371.43 Purity: 99% Optical purity: 98.1% e.e. Soluble in DMSO Description Specific inhibitor of Ack1 tyrosine kinase (also known as TNK2); AIM-100 inhibits Ack1 activity and also suppresses androgen receptor (AR) Tyr(267) phosphorylation and its recruitment to the ATM enhancer (Ack1/AR/ATM signaling) References Certificates Categories Extra info K Mahajan et al. Effect of Ack1 tyrosine kinase inhibitor on ligand-independent androgen receptor activity. Prostate. 2010, 70(12), 1274-1285. K Mahajan et al. Ack1 mediated androgen receptor phosphorylation modulates radiation resistance in castration resistant prostate cancer. J. Biol. Chem. 2012, 287(26), 22112-22122. K Mahajan, NP Mahajan. Shepherding AKT and androgen receptor by Ack1 tyrosine kinase. J. Cell. Physiol. 2010, 224, 327–333. Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology Endocrinology ACK1 EC 2.7.10.2 Specific inhibitor of Ack1 tyrosine kinase (also known as TNK2) Chemical name (S)-5,6-diphenyl-N-((tetrahydrofuran-2-yl)methyl)furo[2,3-d]pyrimidin-4-amine Parent CAS No. [873305-35-2] Order Size Unit Price Stock 5 mg €95.00 In Stock |
| 产品价格 | 现货询价，电话：010-67529703 |
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| 产品品牌 | axonmedchem |
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AIM 100Axon 2031 CAS [873305-35-2] MF C23H21N3O2
Description
Specific inhibitor of Ack1 tyrosine kinase (also known as TNK2); AIM-100 inhibits Ack1 activity and also suppresses androgen receptor (AR) Tyr(267) phosphorylation and its recruitment to the ATM enhancer (Ack1/AR/ATM signaling)
Specific inhibitor of Ack1 tyrosine kinase (also known as TNK2)
Chemical name(S)-5,6-diphenyl-N-((tetrahydrofuran-2-yl)methyl)furo[2,3-d]pyrimidin-4-amine Parent CAS No.[873305-35-2] |
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