| 产品名称 | AZD 3463 |
| 产品货号 | Axon 2153 CAS [1356962-20-3] MF C24H25ClN6OMW 448.95 Purity: 99% Soluble in 0.1N HCl(aq) and DMSO Description Potent inhibitor of Anaplastic Lymphoma Kinase (ALK) and IGF1R; AZD3463 is potent in ALK-driven preclinical models and in a variety of crizotinib-resistant models References Certificates Categories Extra info Discovery of AZD3463 as a Novel ALK/IGFR Dual Inhibitor and its Ability in Overcoming Acquired Resistance to Crizotinib. Presented by B Yang at 8th Protein Kinases in Drug Discovery 2013, Boston USA. Concurrent roles for IGF1R and EGFR in driving acquired resistance to crizotinib and ability to overcome with a combination of the ALK/IGF1R inhibitor AZD3463 and Iressa. Abstr. 4465 presented by L Drew et al. AACR Annual Meeting 2013 Washington DC USA. Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology ALK Endocrinology TGF-β RTK class II and XIX; EC 2.7.10.1 Potent inhibitor of ALK and IGF1R Chemical name N-(4-(4-aminopiperidin-1-yl)-2-methoxyphenyl)-5-chloro-4-(1H-indol-3-yl)pyrimidin-2-amine Parent CAS No. [1356962-20-3] Order Size Unit Price Stock 5 mg €105.00 In Stock |
| 产品价格 | 现货询价，电话：010-67529703 |
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| 产品品牌 | axonmedchem |
| 产品概述 | |
| 产品详情 |
AZD 3463Axon 2153 CAS [1356962-20-3] MF C24H25ClN6O
Description
Potent inhibitor of Anaplastic Lymphoma Kinase (ALK) and IGF1R; AZD3463 is potent in ALK-driven preclinical models and in a variety of crizotinib-resistant models
Potent inhibitor of ALK and IGF1R
Chemical nameN-(4-(4-aminopiperidin-1-yl)-2-methoxyphenyl)-5-chloro-4-(1H-indol-3-yl)pyrimidin-2-amine Parent CAS No.[1356962-20-3] |
| 产品资料 |
