| 产品名称 | OSI 906 - Linsitinib |
| 产品货号 | Axon 1702 CAS [867160-71-2] MF C26H23N5OMW 421.49 Purity: 99% Soluble in DMSO Description Highly potent, orally efficacious and highly selective, dual ATP-competitive tyrosine kinase inhibitor of insulin-like growth factor-1 receptor (IGF-1R) (IC50: 35 nM) and insulin receptor (IR) (IC50: 75 nM) References Certificates Categories Extra info MJ Mulvihill et al. Discovery of OSI-906: a selective and orally efficacious dual inhibitor of the IGF-1 receptor and insulin receptor. Fut. Med. Chem. 2009, 1(6), 1153-1171. CP Carden et al. Phase I study of intermittent dosing of OSI-906, a dual tyrosine kinase inhibitor of insulin-like growth factor-1 receptor (IGF-1R) and insulin receptor (IR) in patients with advanced solid tumors. J. Clin. Oncol. 2010, 28,15s V. M. Macaulay et al. Phase I study of OSI-906, dual tyrosine kinase inhibitor of insulin-like growth factor-1 receptor (IGF-1R) and insulin receptor (IR) in combination with erlotinib (E) in patients with advanced (...). J. Clin. Oncol. 2010, 28,15s Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology IGF1R Endocrinology RTK class II; EC 2.7.10.1 IGF1R tyrosine kinase inhibitor Chemical name 3-[8-Amino-1-(2-phenyl-quinolin-7-yl)-imidazo[1,5-a]pyrazin-3-yl]-1-methyl-cyclobutanol Parent CAS No. [867160-71-2] Order Size Unit Price Stock 2 mg €85.00 In Stock |
| 产品价格 | 现货询价，电话：010-67529703 |
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| 产品品牌 | axonmedchem |
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OSI 906 - LinsitinibAxon 1702 CAS [867160-71-2] MF C26H23N5O
Description
Highly potent, orally efficacious and highly selective, dual ATP-competitive tyrosine kinase inhibitor of insulin-like growth factor-1 receptor (IGF-1R) (IC50: 35 nM) and insulin receptor (IR) (IC50: 75 nM)
IGF1R tyrosine kinase inhibitor
Chemical name3-[8-Amino-1-(2-phenyl-quinolin-7-yl)-imidazo[1,5-a]pyrazin-3-yl]-1-methyl-cyclobutanol Parent CAS No.[867160-71-2] |
| 产品资料 |
