产品名称 | ASP 3026 |
产品货号 | Axon 2005 CAS [1097917-15-1] MF C29H40N8O3SMW 580.74 Purity: 99% Soluble in 0.1N HCl(aq) and DMSO Description Selective inhibitor of the oncogenic fusion kinase EML4-ALK; ASP3026 has a broad safety margin and inhibitory activity at the gatekeeper mutation; potential agent in EML4-ALK fusion positive NSCLC patients, that have relapsed to Crizotinib (Axon 1660) References Certificates Categories Extra info S Kuromitsu et al. Abstract A227: Antitumor activities of ASP3026 against EML4-ALK-dependent tumor models. Mol. Cancer Ther. 2011, 10, 11, S1. J de Lartigue. ALK Inhibitors: Moving Rapidly From Discovery to Clinical Approval and Beyond. Onclive 2013. Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology Oncogene Fusion Proteins TGF-β EC 2.7.10.1 ALK ALK Inhibitor of the oncogenic fusion kinase EML4-ALK Chemical name N2-(2-(isopropylsulfonyl)phenyl)-N4-(2-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)phenyl)-1,3,5-triazine-2,4-diamine Parent CAS No. [1097917-15-1] Order Size Unit Price Stock 2 mg €80.00 In Stock |
产品价格 | 现货询价,电话:010-67529703 |
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产品品牌 | axonmedchem |
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ASP 3026Axon 2005 CAS [1097917-15-1] MF C29H40N8O3S
DescriptionSelective inhibitor of the oncogenic fusion kinase EML4-ALK; ASP3026 has a broad safety margin and inhibitory activity at the gatekeeper mutation; potential agent in EML4-ALK fusion positive NSCLC patients, that have relapsed to Crizotinib (Axon 1660)
Inhibitor of the oncogenic fusion kinase EML4-ALK
Chemical nameN2-(2-(isopropylsulfonyl)phenyl)-N4-(2-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)phenyl)-1,3,5-triazine-2,4-diamine Parent CAS No.[1097917-15-1] |
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