产品名称 Stemregenin 1 - SR1
产品货号 Axon 1865 CAS [1227633-49-9] MF C24H23N5OSMW 429.54 Purity: 99% Soluble in DMSO Description Aryl hydrocarbon receptor (AHR) antagonist that promotes the self-renewal of human hematopoietic stem cells (HSC) in culture. SR1 promotes the ex vivo expansion of CD34+ cells. Culture of HSCs with SR1 led to a 50-fold increase in cells expressing CD34 and a 17-fold increase in cells that retain the ability to engraft immunodeficient mice References Certificates Categories Extra info AE Boitano et al. Aryl hydrocarbon receptor antagonists promote the expansion of human hematopoietic stem cells. Science 2010, 329, 1345-1348.    G Sauvageau and RK Humphries. The blood stem cell Holy Grail? Science 2010, 329, 1291-1292. Certificate of Analysis Material Safety Data Sheet Cardiovascular Cell Signaling & Oncology Diabetes & Metabolism Immunology Stem Cell AHR Transcription Factors TF class 1.2 Aryl hydrocarbon receptor (AHR) antagonist Chemical name 4-(2-(2-(benzo[b]thiophen-3-yl)-9-isopropyl-9H-purin-6-ylamino)ethyl)phenol Parent CAS No. [1227633-49-9] Order Size Unit Price Stock 10 mg €105.00 In Stock
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Stemregenin 1 - SR1

Based on 15 reference(s) in Google Scholar 8 10 15

Axon 1865

CAS [1227633-49-9]

MF C24H23N5OS
MW 429.54

  • Purity: 99%
  • Soluble in DMSO

Stemregenin 1

Description

Aryl hydrocarbon receptor (AHR) antagonist that promotes the self-renewal of human hematopoietic stem cells (HSC) in culture. SR1 promotes the ex vivo expansion of CD34+ cells. Culture of HSCs with SR1 led to a 50-fold increase in cells expressing CD34 and a 17-fold increase in cells that retain the ability to engraft immunodeficient mice
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