产品名称 GS 39783
产品货号 Axon 1820 CAS [39069-52-8] MF C15H23N5O2SMW 337.44 Purity: 99% Moderately soluble in DMSO Description Positive allosteric modulator at GABAB receptor References Certificates Categories Extra info S Urwyler et al. N,N'-Dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamine (GS39783) and structurally related compounds: novel allosteric enhancers of gamma-aminobutyric acidB receptor function. J. Pharmacol. Exp. Ther. 2003, 307(1), 322-330.    C Mombereau et al. Genetic and pharmacological evidence of a role for GABA(B) receptors in the modulation of anxiety- and antidepressant-like behavior. Neuropsychopharmacol. 2004, 29(6), 1050-1062.    P Maccioni et al. Reducing effect of the positive allosteric modulator of the GABA(B) receptor, GS39,783, on alcohol self-administration in alcohol-preferring rats. Psychopharmacology (Berlin). 2007, 193(2), 171-178.    NE Paterson et al. Positive modulation of GABA(B) receptors decreased nicotine self-administration and counteracted nicotine-induced enhancement of brain reward function in rats. J. Pharmacol. Exp. Ther. 2008, 326(1), 306-314.  Certificate of Analysis Material Safety Data Sheet CNS Pain & Inflammation GABA-B C2 PAM of GABA-B Receptor Chemical name N4,N6-dicyclopentyl-2-(methylthio)-5-nitropyrimidine-4,6-diamine Parent CAS No. [39069-52-8] Order Size Unit Price Stock 10 mg €99.00 In Stock
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