产品名称

BH3I 1 - BHI 1

产品货号

Axon 1828 CAS [300817-68-9] MF C15H14BrNO3S2MW 400.31 Purity: 99% Soluble in 0.1N NaOH(aq) and DMSO Description Cell permeable antitumor agent targeting Bcl-2 family protein, more specifically as Bcl-xL antagonist; apoptosis inducer, inducing a dose- and time-dependent apoptosis in H460 and H1792 cells References Certificates Categories Extra info W Roa et al. Enhancement of radiation sensitivity with BH3I-1 in non-small cell lung cancer. Clin. Invest. Med. 2005, 28(2), 55-63. S Shangary and DE Johnson. Recent advances in the development of anticancer agents targeting cell death inhibitors in the Bcl-2 protein family. Leukemia 2003, 17, 1470–1481. Certificate of Analysis Material Safety Data Sheet Apoptosis Cell Cycle Regulation Cell Signaling & Oncology Bcl Inhibitor of Bcl-2 family protein Chemical name 2-(5-(4-bromobenzylidene)-4-oxo-2-thioxothiazolidin-3-yl)-3-methylbutanoic acid Parent CAS No. [300817-68-9] Order Size Unit Price Stock 10 mg €125.00 In Stock

产品价格

现货询价，电话：010-67529703

产品规格

产品品牌

axonmedchem

产品概述

产品详情

BH3I 1 - BHI 1

Based on 12 reference(s) in Google Scholar 9 10 12

Axon 1828

CAS [300817-68-9]

MF C15H14BrNO3S2
MW 400.31

Purity: 99%
Soluble in 0.1N NaOH(aq) and DMSO

BH3I 1

Description

Cell permeable antitumor agent targeting Bcl-2 family protein, more specifically as Bcl-xL antagonist; apoptosis inducer, inducing a dose- and time-dependent apoptosis in H460 and H1792 cells

W Roa et al. Enhancement of radiation sensitivity with BH3I-1 in non-small cell lung cancer. Clin. Invest. Med. 2005, 28(2), 55-63.

S Shangary and DE Johnson. Recent advances in the development of anticancer agents targeting cell death inhibitors in the Bcl-2 protein family. Leukemia 2003, 17, 1470–1481.

Inhibitor of Bcl-2 family protein

Chemical name

2-(5-(4-bromobenzylidene)-4-oxo-2-thioxothiazolidin-3-yl)-3-methylbutanoic acid

Parent CAS No.

[300817-68-9]

产品资料