| 产品名称 | YM 155 |
| 产品货号 | Axon 1639 CAS [781661-94-7] MF C20H19BrN4O3MW 443.29 Purity: 98% Soluble in DMSO Description Small molecule survivin suppresant or inhibitor; YM155 suppressed expression of survivin and induced apoptosis in p53-deficient human HRPC cell lines at 10 nmol/L References Certificates Categories Extra info A Kita et al. Survivin suppressant: a promising target for cancer therapy and pharmacological profiles of YM155. Nippon Yakurigaku Zasshi 2010, 136(4), 198-203. T Iwasa et al. Marked anti-tumour activity of the combination of YM155, a novel survivin suppressant, and platinum-based drugs. Br. J. Cancer 2010, 103(1),36-42. T Nakahara et al. YM155, a Novel Small-Molecule Survivin Suppressant, Induces Regression of Established Human Hormone-Refractory Prostate Tumor Xenografts. Cancer Res. 2007, 67, 8014-8021. R Gonzalez et al. A phase II study of YM155, a novel survivin suppressant, administered by 168 hour continuous infusion in patients with unresectable stage III or stage IV melanoma. J. Clin. Oncol. 2007, 25(18S), 8538. T Satoh et al. Phase I Study of YM155, a Novel Survivin Suppressant, in Patients with Advanced Solid Tumors. Clin. Cancer Res. 2009, 15, 3872. Certificate of Analysis Material Safety Data Sheet Apoptosis Cell Cycle Regulation Cell Signaling & Oncology Ubiquitin IAP Survivin suppressant Chemical name 1-(2-methoxyethyl)-2-methyl-4,9-dioxo-3-(pyrazin-2-ylmethyl)-4,9-dihydro-1H-naphtho[2,3-d]imidazol-3-ium bromide Parent CAS No. [N.A.] Order Size Unit Price Stock 5 mg €95.00 In Stock |
| 产品价格 | 现货询价，电话：010-67529703 |
| 产品规格 | |
| 产品品牌 | axonmedchem |
| 产品概述 | |
| 产品详情 |
YM 155Axon 1639 CAS [781661-94-7] MF C20H19BrN4O3
Description
Small molecule survivin suppresant or inhibitor; YM155 suppressed expression of survivin and induced apoptosis in p53-deficient human HRPC cell lines at 10 nmol/L
Survivin suppressant
Chemical name1-(2-methoxyethyl)-2-methyl-4,9-dioxo-3-(pyrazin-2-ylmethyl)-4,9-dihydro-1H-naphtho[2,3-d]imidazol-3-ium bromide Parent CAS No.[N.A.] |
| 产品资料 |
