产品名称 | SR 3576 |
产品货号 | Axon 2365 CAS [1164153-22-3] MF C27H27N5O5MW 501.53 Purity: 99% Soluble in DMSO Description Very potent JNK3 inhibitor (IC50 value 7 nM) with >2800-fold selectivity over p38 (p38 IC50 value >20 μm) and a cell-based potency of ca. 1 μM. References Certificates Categories Extra info T. Kamenecka et al. Structure-activity relationships and X-ray structures describing the selectivity of aminopyrazole inhibitors for c-Jun N-terminal kinase 3 (JNK3) over p38. J. Biol. Chem. 2009, 284, 12853-12861. Certificate of Analysis Material Safety Data Sheet Apoptosis Cell Signaling & Oncology Immunology Pain & Inflammation MAPK (JNK) p53-Tumor Suppression NF-κB MAPK EC 2.7.11.24 Very potent JNK3 inhibitor with >2800-fold selectivity over p38 Chemical name 3-(4-(3-m-tolylureido)-1H-pyrazol-1-yl)-N-(3,4,5-trimethoxyphenyl)benzamide Parent CAS No. [1164153-22-3] Order Size Unit Price Stock 10 mg €135.00 In Stock |
产品价格 | 现货询价,电话:010-67529703 |
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产品品牌 | axonmedchem |
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SR 3576Axon 2365 CAS [1164153-22-3] MF C27H27N5O5
Description
Very potent JNK3 inhibitor (IC50 value 7 nM) with >2800-fold selectivity over p38 (p38 IC50 value >20 μm) and a cell-based potency of ca. 1 μM.
Very potent JNK3 inhibitor with >2800-fold selectivity over p38
Chemical name3-(4-(3-m-tolylureido)-1H-pyrazol-1-yl)-N-(3,4,5-trimethoxyphenyl)benzamide Parent CAS No.[1164153-22-3] |
产品资料 |