产品名称 SR 3576
产品货号 Axon 2365 CAS [1164153-22-3] MF C27H27N5O5MW 501.53 Purity: 99% Soluble in DMSO Description Very potent JNK3 inhibitor (IC50 value 7 nM) with >2800-fold selectivity over p38 (p38 IC50 value >20 μm) and a cell-based potency of ca. 1 μM. References Certificates Categories Extra info T. Kamenecka et al. Structure-activity relationships and X-ray structures describing the selectivity of aminopyrazole inhibitors for c-Jun N-terminal kinase 3 (JNK3) over p38. J. Biol. Chem. 2009, 284, 12853-12861. Certificate of Analysis Material Safety Data Sheet Apoptosis Cell Signaling & Oncology Immunology Pain & Inflammation MAPK (JNK) p53-Tumor Suppression NF-κB MAPK EC 2.7.11.24 Very potent JNK3 inhibitor with >2800-fold selectivity over p38 Chemical name 3-(4-(3-m-tolylureido)-1H-pyrazol-1-yl)-N-(3,4,5-trimethoxyphenyl)benzamide Parent CAS No. [1164153-22-3] Order Size Unit Price Stock 10 mg €135.00 In Stock
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SR 3576

Based on 18 reference(s) in Google Scholar 9 10 18

Axon 2365

CAS [1164153-22-3]

MF C27H27N5O5
MW 501.53

  • Purity: 99%
  • Soluble in DMSO

SR 3576

Description

Very potent JNK3 inhibitor (IC50 value 7 nM) with >2800-fold selectivity over p38 (p38 IC50 value >20 μm) and a cell-based potency of ca. 1 μM.
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