产品名称 ZCL 278
产品货号 Axon 2138 CAS [587841-73-4] MF C21H19BrClN5O4S2MW 584.89 Purity: 98% Soluble in DMSO Description Selective Cdc42 GTPase inhibitor. ZCL 278 specifically targets Cdc42–ITSN interaction and inhibits Cdc42-mediated cellular processes, thus providing a powerful tool for research of Cdc42 subclass of Rho GTPases in human pathogenesis. ZCL 278 reduces the perinuclear accumulation of active Cdc42 in contrast to NSC 23766 (Axon 1578), a selective Rac inhibitor. References Certificates Categories Extra info A Friesland et al. Small molecule targeting Cdc42–intersectin interaction disrupts Golgi origanization and suppresses cell motility. Proc. Natl Acad. Sci. USA. 2013, 110, 1261-1266.  Certificate of Analysis Material Safety Data Sheet Cell Cycle Regulation Cell Signaling & Oncology Stem Cell Cdc42 p53-Tumor Suppression EC 3.6.5.2 Cdc42 GTPase inhibitor, targeting Cdc42–ITSN interaction Chemical name 2-(4-bromo-2-chlorophenoxy)-N-(4-(N-(4,6-dimethylpyrimidin-2-yl)sulfamoyl)phenylcarbamothioyl)acetamide Parent CAS No. [587841-73-4] Order Size Unit Price Stock 10 mg €105.00 In Stock
产品价格 现货询价,电话:010-67529703
产品规格
产品品牌 axonmedchem
产品概述
产品详情

ZCL 278

Based on 18 reference(s) in Google Scholar 9 10 18

Axon 2138

CAS [587841-73-4]

MF C21H19BrClN5O4S2
MW 584.89

  • Purity: 98%
  • Soluble in DMSO

ZCL 278

Description

Selective Cdc42 GTPase inhibitor. ZCL 278 specifically targets Cdc42–ITSN interaction and inhibits Cdc42-mediated cellular processes, thus providing a powerful tool for research of Cdc42 subclass of Rho GTPases in human pathogenesis. ZCL 278 reduces the perinuclear accumulation of active Cdc42 in contrast to NSC 23766 (Axon 1578), a selective Rac inhibitor.

产品资料